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Zebrafish (Beijing) Technology Co., Ltd
Nanopore third-generation sequencing fully automated workstation
NegotiableUpdate on 05/07
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Overview
ElysION is a fully automated workstation for third-generation nanopore sequencing, including sample preparation equipment, MinION Mk1D nanopore sequencer, and supporting ElysION MinION control unit. The sample preparation equipment workbench integrates MinION Mk1D, and the control unit is pre installed with sequencing software and Linux system. It connects to the sample preparation equipment via Ethernet to achieve bidirectional data transmission. It can control sequencing, store files with a capacity of 6.7Tb, and perform downstream analysis through bioinformatics processes, providing end-to-end services from sample to result.
Product Details
1、 Product Overview
ElysION is launched by Oxford Nanopore TechnologyNanopore third-generation sequencing fully automated workstation，providefromFully automated "sample to result" nanopore sequencing complete solutionSpecially designed to simplify the workflow of genomics, by integrating the entire process module, various laboratories can conduct efficient sequencing research without complex operations.
The core of this solution consists of three parts: one is the integration of liquid processing functionsSample preparation equipmentIt can automate the pre-processing steps such as nucleic acid extraction and library construction without the need for manual intervention; The second is integrated into the preparation equipment workbenchMinION Mk1D sequencerContinuing the advantage of nanopore length and reading length; Thirdly, it is complementaryElysion MinION control unitAs a central hub to achieve full process control.
Nanopore third-generation sequencing fully automated workstationThe control unit is equipped with a Linux system and sequencing software, which enables bidirectional data transmission with the preparation equipment via Ethernet. It has a 6.7Tb storage capacity that can retain massive sequencing files, and a built-in bioinformatics process that can automatically complete base recognition, sequence analysis, and generate reports, truly achieving end-to-end service from sample to result. Its automation feature significantly reduces the operational threshold, with a fast turnaround time of 4 hours from cracking solution to report. It can process 1-96 samples in a single round and is suitable for different experimental scales.
2、 Core Technology
Oxford Nanopore sequencing is based on nanopore single-molecule detection technology. During sequencing, nucleic acid molecules (DNA/RNA) are driven by motor enzymes to pass through the nanopore in a single stranded form, one base at a time. When a base passes through, it changes the current intensity inside the nanopore, and there are differences in the current signals corresponding to different bases (A, T, C, G) and modified bases. The device captures these current changes in real time and uses MinKnow ™ Convert the software into base sequences to achieve direct sequencing of single molecules. This technology does not require PCR amplification, can retain base modification information, and has unlimited read length, enabling real-time data analysis and combining portability and efficiency.
3、 Core performance advantages
One stop intelligent solution, zero professional thresholdImplementing genomics research with a single solution without the need for professional genomics knowledge; Equipped with an intuitive "set and run" workflow, the operation is simple and easy to understand, and non professionals can quickly get started.
Fully automated integration, widely usedAs a fully automated sequencing solution, the entire process from sample processing to result output can be completed without human intervention; Adapting to various application scenarios, it can meet the sequencing needs of different fields and has strong flexibility.
Simplify laboratory processes, reduce costs and improve efficiencySignificantly simplifying the laboratory sequencing operation process and reducing manpower investment time; Simultaneously reducing experimental costs and personnel training resource consumption, saving operating expenses for the laboratory.
No need for sample batch, quick results acquisitionSupport starting sequencing tasks at any time without waiting for sample batch, significantly reducing the experimental period; Can quickly generate sequencing results, helping to efficiently promote scientific research and testing work.
Ensure experimental consistency and adapt to routine testingThe equipment design supports standardized and routine experimental operations, which can reduce human operation errors, ensure the stability and consistency of experimental results, and is suitable for high-frequency routine detection scenarios.
4、 Application Fields
Infectious disease researchNo need for sample batching, sequencing of sudden infectious disease pathogens (such as viruses and influenza) can be initiated at any time. The fully automated process produces preliminary results within 4 hours, helping to quickly trace mutations, monitor transmission pathways, and provide timely data support for prevention and control decisions.
Microbial isolation and sequencingAdapted for sequencing isolated strains of bacteria and fungi, the "set and run" process does not require professional genomics knowledge and can efficiently complete strain identification and drug resistance gene screening, simplifying laboratory operations while ensuring consistency of results, making it suitable for building microbial resource libraries.
Plasmid validationFully automated processing avoids manual operation errors and can quickly verify the insertion fragments and sequence integrity of recombinant plasmids, reducing manpower time and training costs, and adapting to the conventional plasmid quality control requirements in the fields of biopharmaceuticals and genetic engineering.
Human GenomicsAs a one-stop solution, it supports sequencing of specific regions of the human genome (such as disease-related loci) without the need for complex process design. With a 6.7Tb storage capacity, it can retain a large amount of sample data and assist research laboratories in conducting genetic disease association analysis and other research.
cancer researchIt can quickly detect gene mutations and structural variations in tumor tissue samples without batch waiting. The fully automated process reduces human error and provides efficient sequencing support for cancer typing and targeted drug screening, suitable for clinical research and personalized diagnosis and treatment research.
MetagenomicsAdapting to environmental and intestinal metagenomic sample analysis, the entire process is automated to process complex samples, efficiently analyzing microbial community structure and functional genes, simplifying experimental procedures, ensuring the stability of multi sample detection results, and assisting microbial community research.
Plant and animal researchSupport gene sequencing of crop, livestock and other animal and plant samples, such as disease resistance gene screening and breeding related locus detection. The "zero threshold" operation is suitable for agricultural research laboratories, and research can be carried out without the need for a professional team, reducing project costs and cycles.
5、 Equipment specifications
| specification | ElysION Sample preparation equipment |
ElysION MinION control unit |
ElysION MinION Mk1D |
|---|---|---|---|
| model | ELY-SPPD001 | ELY-CMU001 | MIN-101D |
| Supply voltage (V) | 200-240 AC ±10%（50/60 Hz） | 200-240 AC ±10%（50/60 Hz） | 5 DC |
| Rated current (A) | 10 | 10 | 1.5 |
| Rated power (VA) | 2300 | 750 | 7.5 |
| Dimensions (height x width x depth, mm) | 1096 (1428 when the door is open) × 1190 × 783 | 300×180×340 | 13×55×125 |
| Weight (kg) | 243 | 9 | 0.13 |
| Install port |
1 x power supply connection Port 1 x Ethernet interface 1 x USB-C 3.0 interface |
1 x power interface 2 x HDMI interface 6 x DisplayPort interface 2 x Ethernet interface 4 x USB-A 2.0 interface 1 x USB-C 3.0 interface |
1 x USB-C 3.0 interface |
| preinstalled software | Windows 10BotQL | Ubuntu 20.04 Sequencing Software | MinION driver program |
| Calculate specifications |
1 x Intel CPU 16 GB of memory 500 GB SSD storage |
1 x NVIDIA Ampere Series GPU 1 x Intel CPU (20 cores) 64 GB of memory 6.7 TB SSD storage |
Nothing |
| Ambient temperature | +5 ℃ to+40 ℃ | +5 ℃ to+40 ℃ | +5 ℃ to+40 ℃ |
| humidity | Relative humidity ranging from 30% to 60% (without condensation) | Relative humidity ranging from 30% to 75% (without condensation) | Relative humidity ranging from 30% to 75% (without condensation) |
| Sequencing temperature | Design sequencing environment temperature:+20 ℃ to+27 ℃ | Not applicable (N/A) |
Zebrafish (Beijing) Technology Co., Ltd. provides you with information on instrument parameters, prices, selection, technical principles, etc. For more information, please feel free to contact us.
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