Multi functional microplate detection system for cell imaging

1、 Instrument Introduction

• Hybrid dual path detection: bandwidth adjustable four grating+high-performance filter system, balancing wavelength flexibility and ultra-high sensitivity, supporting absorption, fluorescence, and emission FRET/BRET、HTRF、 Fluorescence polarization and Alpha detection full mode.

• Dual mode microscopy imaging: inverted fluorescence (6-position Olympus objective, 4 independent fluorescence channels, large field camera)+upright transmission/reflection light, compatible with 2D/3D cells, organoids, tissue sections, model organisms, and opaque samples.

• Dual autofocus: image focusing adapted to 3D thick samples; Laser focusing speeds up by about 50%, low light toxicity, and 96 well plates provide faster and more stable imaging.

• XYZ advanced imaging: Z-stack layer scanning, Montage large field of view stitching, and high-definition presentation of the entire field and layer.

• Exclusive environmental control for live cells: 4-Zone fanless uniform temperature control+top anti condensation, external CO ₂/O ₂ precise regulation, supporting long-term kinetic experiments under normoxic/hypoxic conditions.

• High throughput automation: AutoEasy fully automated workflow, Hitpicking intelligent target screening, batch/fixed-point dual imaging mode, unmanned and efficient operation.

• Gen5 all-in-one software: fully built-in for shooting, processing, analysis, and image output, providing one-stop services for cell recognition, subpopulation analysis, batch statistics, and paper level output.

• Modular and scalable: supports automatic sampler, storage board, fully automatic scratch tester, CB high-throughput integration system, and does not require machine replacement with project upgrades.

• One machine with multiple functions, bidding farewell to equipment stacking: imaging instrument+enzyme-linked immunosorbent assay reader+upright microscope are integrated into one, with a coherent process, data homology, and optimized space and cost.

• Dual optical paths complement each other strongly: the grating is flexible in scanning spectra, and the filter is highly sensitive, without compromising between flexibility and accuracy.

• Living cells are friendly to the end: temperature control is stable, there is no phototoxicity, anti condensation, gas is controllable, and long-term observation of cell state is more stable.

• High throughput and intelligence: Hitpicking, fully automated operation, batch analysis, significantly reducing ineffective workload.

• Modularization can grow: the basic configuration is sufficient, and it can be expanded as needed in the future. It can adapt to long-term project upgrades with one investment.

• Minimalist operation and hardcore output: easy for beginners to learn, efficient for experienced professionals, with images and data directly meeting the requirements for journal publication.

• Cell biology: cell proliferation/toxicity/apoptosis, cell cycle, migration and invasion, autophagy, signaling pathways, calcium flow, mitochondrial membrane potential.

• 3D and organoids: organoid morphology, growth kinetics, 3D layer scan imaging, drug response assessment.

• High throughput drug screening: compound screening, kinase/enzyme activity detection, reporter genes, ion channels, Hitpicking precision target imaging.

• Development/Neurology/Immunology: neurite outgrowth, plaque formation, phagocytosis, viral infection, stem cell differentiation, cell activation.

• Pathology and tissue imaging: H&E/IHC sections, cell slides, clone counting ELISpot、 Plant samples, Transwell/microcarrier observations.

• Biochemical and molecular testing: protein/nucleic acid quantification, enzyme kinetics, molecular interactions FRET/HTRF/BRET、AlphaScreen。

• Long term live cells: time-lapse imaging, hypoxia model, metabolic kinetics, cell growth tracking, scratch healing.

Zebrafish (Beijing) Technology Co., Ltd. provides you with information on instrument parameters, prices, selection, technical principles, etc. For more information, please feel free to contact us.