Dynamic gastrointestinal in vitro simulation of digestive system

Dynamic gastrointestinal in vitro simulation of digestive system

1.Each simulated reactor is equipped with an independent servo electric stirrer module for simulating reactor agitation and creep.

2Each simulated reactor is equipped with a flow meter and inert gas is introduced

Implement anaerobic conditions in each simulated reactor.

3.The entire system can simulate single feeding and digestion of monogastric animals, as well as monogastric animals1 Eating multiple times a day or frequently over multiple days,

4.Can simulate simultaneously 5 Users can also choose any number of parts to simulate, and they can make their own choices.

5.During the entire simulation period, blood glucose and glycemic index were close to the levels in monogastric animals,compatibility90%Above, metabolism and absorption of nutrients such as lactate85%Above

6.The temperature control adopts a semiconductor waterless temperature control method, which is controlled byPIDController control implementation 37Constant temperature control at ℃. Water free temperature control does not require external water sources or connecting inlet and outlet pipelines. Temperature electrodes monitor whether the temperature inside the tank is constant. And it can achieve the function of recording process temperature,

7.The system can simulate the stomach, small intestine, ascending colon, transverse colon, and descending colon5 Five parts are interconnected to form a dynamic system, with five reactors integrated into the same systemABSInside the plastic box, it is equipped with a top cover and a large window. The top cover can be opened upwards to provide insulation and dust prevention for the entire system. Each reactor is configured separately5/5/4/4/4A pump.

8.Add an absorption pump, which should work continuously in both directions according to the absorption laws of the human digestive organs. It should also be equipped with an absorption valve that simulates the human intestinal wall to absorb sugars, amino acids, peptides, and small molecule proteins; And ensure that the interface for online monitoring of this nutrient component can be expanded in the future, and connected to the main control system. The entire system runs automatically and continuously simulates the process of human digestion and absorption.

Function of intestinal simulation control system

1.Freely expandable up, down, left, right, interface 360 Degree rotation embedded installation15Wide screen color LCD touch screen, programmable controller, capable of simultaneous detection and control 5 Taiwan1LCorresponding parameters of the simulator; And retain the ability to upgrade to more channels (at least) 2 The interface of a channel. The software comes with its own upper computer software and mobile phoneAPPRemote control of the end allows the purchaser to remotely monitor and control operating parameters through upper computer software on the office computer; The purchaser can purchase at any time Anywhere, anytime via mobile phoneAPPRemote monitoring and control of operating parameters at the end.

2.The user interface provides a graphical overview of the simulator unit, which should be consistent with the appearance and position of the stomach, small intestine, and ascending and descending colon. At the same time, the instrument realizes dual screen control, which separates the expression of parameters and process display, making it easier for the purchaser to build and observe the experiment more intuitively.

3.The footer function menu buttons include: home page, trend, calibration, control, recipe, historical data, user management, alarm, one click settings, and retrieval of stored recipes. Click on each function button to access the corresponding function interface.

4.Management interface: Users can be added, copied, modified, deleted, and logged out.

5.At least pre stored in the software system 5 A formula is used for different simulation objects and processes, allowing for one click retrieval of formulas, direct parameter calling, and direct experiment initiation, saving time and effort. At the same time, the purchaser can also customize and create formulas to facilitate data retrieval and horizontal comparison in the future. Data export format is optionalexcelandpdfFormat.

Main Performance Description

1.Simulator:1000mL， 5 group Liquid loading coefficient60~80%，

Material: borosilicate glass andSUS316LStainless steel combination.

2.Supplement bottle 13 Only,500ml.

3.Total collection bottle at the end before reaction 2 Only, volume5L.

4.Control range:0~1000rpmAccuracy:1%Electric mixing (independently controlled)+Specialized mixing blade.

5.Water free temperature control system, control range:37℃； Accuracy ±0.3℃； Each jar is independently temperature controlled and equipped with its ownPT100Temperature electrode.

6Precision fluid replacement system module:5 Configure each simulator separately5/5/4/4/4A micro variable speed peristaltic pump is integrated into the host controller.

7.pHControl module: equipped with 5 Support high-temperature sterilizationpHsensor,Online detection and controlpH.

8.Free warranty after equipment acceptance1Year (excluding consumables such as gaskets, silicone tape joints, etc.).

9.After the warranty period,Suppliers can also provide comprehensive technical support and services.

Quantity of configuration

Each set includes 2 Group in vitro intestinal simulation system, capable of conducting parallel control group

experiment