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Heretic multi armed polyethylene glycol (NHS) 3-4ARM-PEG-Mal
NegotiableUpdate on 05/06
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Overview
Heterogeneous multi armed polyethylene glycol (NHS) 3-4ARM-PEG-Mal $r $n targeted coupling: The Maleimide end can react with the thiol group of targeted ligands (such as antibodies and peptides) to achieve precise drug targeting. $r $n Multi drug Carrier Construction: NHS ester end can react with amino groups of different drugs or functional molecules to construct multifunctional or multi drug composite carriers. $r $n improves drug stability and circulation time: PEG backbone increases water solubility, reduces immune clearance, and increases drug half-life in vivo. $r $n controllable release and intelligent response design: By designing degradable links, specific physiological conditions can be achieved
Product Details
Heretic multi armed polyethylene glycol (NHS) 3-4ARM-PEG-Mal
Key product information
Chinese name:Four arm polyethylene glycol, three arm active lipid, one arm maleimide
English name:4arm PEG，1arm-Maleimide，3arm-NHS
Abbreviation:(NHS)3-4ARM-PEG-Maleimide
Brand: MeloPEG Technology
Structure:
Purity:Over 95%
定制： The NHS and The proportion of MAL can be customized at any ratio
Molecular weight: PEG2K、PEG5K、PEG10K、PEG20k， Other molecular weight consultation customer service
Precautions
Keep dry
Storage conditions
-Freezing and drying below 20 ℃
Heretic multi armed polyethylene glycol (NHS) 3-4ARM-PEG-Mal
application
4ARM PEG Maleimide (1)/NHS (3) refers to a four armed polyethylene glycol (PEG) derivative, in which:
·One arm is attached with a maleimide group, used for reacting with molecules containing thiol groups (- SH);
·Three arms are connected to NHS ester (N-hydroxysuccinimide, N-Hydroxysuccinimide ester）， Used for reactions with molecules containing amino groups (- NH ₂).
Application in drug delivery:
Targeted coupling:Maleimide can react with thiol groups of targeted ligands (such as antibodies and peptides) to achieve precise drug targeting.
Multi drug carrier construction:NHS ester end can react with amino groups of different drugs or functional molecules to construct multifunctional or multi drug composite carriers.
Improve drug stability and circulation time:PEG skeleton increases water solubility, reduces immune clearance, and increases the half-life of drugs in the body.
Controllable release and intelligent response design:By designing biodegradable links, drug release can be achieved under specific physiological conditions, such as reducing environments.
Related directories:
(NH2)3-4ARM-PEG-NHBoc Four arm polyethylene glycol, three arm amino, one arm tert butoxycarbonylamino
(NH2)2-4ARM-PEG-(NHBoc)2 Four arm polyethylene glycol, two arm amino, two arm tert butoxycarbonylamino
(NHBoc)3-4ARM-PEG-NH2 Four arm polyethylene glycol, three arm tert butoxycarbonylamino, one arm amino
(Maleimide)3-4ARM-PEG-COOH Four arm polyethylene glycol, three arm maleimide, one arm carboxyl group
(Maleimide)2-4ARM-PEG-(COOH)2 Four arm polyethylene glycol, two arm maleimide, two arm carboxyl group
(Alkyne)3-4ARM-PEG-NHS Four arm polyethylene glycol, three arm alkynyl, one arm active lipid
(Alkyne)2-4ARM-PEG-(NHS)2 Four arm polyethylene glycol, two arm alkynyl, two arm active lipid
(NHS)3-4ARM-PEG-Alkyne Four arm polyethylene glycol, three arm active lipid, one arm alkynyl group
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