CRGD-PEG-HA tumor targeting peptide polyethylene glycol hyaluronic acid

CRGD-PEG-HA tumor targeting peptide polyethylene glycol hyaluronic acid

1、 Product Overview

CRGD PEG HA (tumor targeting peptide polyethylene glycol hyaluronic acid), also known as HA PEG cRGD (hyaluronic acid polyethylene glycol integrin targeting cyclic peptide), is a three functional block conjugate reagent specially designed for cutting-edge biomedical experiments. It integrates the integrin targeting property of cRGD cyclic peptide, the long cycling stability of PEG chain, and the CD44 receptor affinity of hyaluronic acid, and can achieve precise dual receptor targeted delivery of active substances such as drugs and probes, effectively solving the experimental pain points of insufficient targeting property, poor in vivo stability, and low biocompatibility of traditional carriers. It provides high-performance carrier selection for fields such as tumor research, molecular imaging, and tissue engineering.

2、 Core parameters of the product

Chinese nameTumor targeting peptides -Polyethylene glycol hyaluronic acid

hyaluronic acid -Polyethylene glycol integrin targeted cyclic peptide

English name：cRGD-PEG-HA、HA-PEG-cRGD

PEG molecular weight：1000, 2000, 3400, 5000, 10000

Product characteristics: Semi solid or solid from off white to pale yellow

Inspection ReportProvide nuclear magnetic resonance（NMR and COA detection reports can provide HPLC and MS detection data for peptides

Storage conditions：-Store at a low temperature of 20 ℃, away from light and dry to avoid repeated freezing and thawing, and extend the product's service life

scope of application：The product is only for scientific research and experimental use, and is not used in the fields of human diagnosis and treatment, clinical treatment, and food additives

CRGD-PEG-HA tumor targeting peptide polyethylene glycol hyaluronic acid

3、 Product Features and Application Scenarios

CRGD PEG HA (HA PEG cRGD) is widely used in biomedical research experiments due to its dual targeting and multiple performance advantages. Its cRGD cyclic peptide can specifically recognize integrin receptors highly expressed in tumor blood vessels and tumor cells. The hyaluronic acid fragment targets the CD44 receptor, and dual targeting greatly improves the enrichment efficiency at the lesion site, reducing experimental interference caused by non-specific binding.

inTargeted drug delivery experimentIn addition, it can be used as a surface modifier for carriers such as liposomes, nanoparticles, and micelles, carrying chemotherapy drugs, peptide drugs, gene fragments, etc., to accurately deliver to tumor lesions, reduce the impact of drugs on normal tissues, and improve the accuracy of drug treatment efficacy evaluation in experiments. in分子成像研究In China, probes such as fluorescent dyes and radioactive isotopes can be coupled to achieve highly specific imaging of tumors and vascular lesions, providing reliable tools for early diagnosis of diseases, research on metastasis mechanisms, and dynamic monitoring of therapeutic effects.

inOrganizational Engineering and Regenerative Medicine LaboratoryIt can modify the surface of hydrogel and biological scaffold, promote cell adhesion, proliferation and differentiation through receptor mediated effect, optimize the microenvironment of cell culture, and assist in tissue regeneration, wound repair and other research. In addition, it is also applicable to multiple research directions such as biosensor construction, protein and peptide targeted modification, and gene delivery system optimization, meeting the precise targeting experimental needs in multiple fields.

4、 Shenzhen Meiluo Technology Co., Ltd（MeloPEG Introduction

Shenzhen Meiluo Technology Co., Ltd（MeloPEG focuses on the research, development, production, and sales of PEG derivatives, targeted conjugated materials, and biomedical polymers. Its products cover over a thousand scientific research reagents such as PEGylated phospholipids, targeted peptides PEG, and hyaluronic acid PEG, and can provide customized services for molecular weight, functional groups, and degree of substitution. The company has established long-term cooperation with dozens of universities and research institutes such as Tsinghua University, Peking University, and the Chinese Academy of Sciences, and its product quality has been verified through multiple tests. Capable of quick delivery of spot goods and customized delivery within 7-15 days, providing professional technical support and after-sales Q&A, strictly following the "research only" principle, providing stable, reliable, and high-quality experimental materials for global research teams.

5、 Meiluo Technology HA-PEG series related products

HA-PEG-NHSHyaluronic acid -Polyethylene glycol active ester

HA-PEG-MALHyaluronic acid -Polyethylene glycol maleimide

HA-PEG-FAHyaluronic acid -Polyethylene glycol leaf acid

HA-PEG-DSPEHyaluronic acid -Polyethylene glycol phospholipid

HA-PEG-NH ₂Hyaluronic acid -Polyethylene glycol amino

6. Conclusion

CRGD PEG HA (HA PEG cRGD), as the core dual targeted carrier product of Meiluo Technology, combines the triple advantages of hyaluronic acid, PEG, and cRGD cyclic peptide, breaking through the application limitations of traditional single targeted carriers and providing high-performance solutions for precision tumor therapy, molecular imaging, tissue engineering, and other scientific research experiments. MeloPEG in Shenzhen has always focused on scientific research needs, relying on its * product system, strict quality control standards, efficient supply and after-sales capabilities, to continuously provide high-quality reagents and professional services to global scientific researchers, and to support scientific innovation and breakthroughs in the field of biomedicine.