CRGD PEG HA cRGD targeting peptide polyethylene glycol hyaluronic acid

CRGD PEG HA cyclic RGD peptide polyethylene glycol hyaluronic acid: high-performance targeted functional materials in scientific research field

CRGD-PEG-HA is a targeted coupling material for scientific research launched by Guangzhou Tanshtech. It has excellent self-assembly performance and receptor recognition ability, and can be widely used in nanocarrier construction, biological interface modification, and functional material development. The product, with its stable structure, strong targeting ability, and good water solubility, has become a commonly used reagent in the research of nanotechnology and biomedical materials. The company's product has been cited over a thousand times in scientific research, and is only used for scientific experiments and not for human use.

CRGD PEG HA cRGD targeting peptide polyethylene glycol hyaluronic acid

Core advantages of the product

-Accurate and controllable structure: Covalent coupling process, stable structure without free components, excellent batch repeatability.

-Excellent physical and chemical properties: an amphiphilic molecule that is easily soluble in solvents such as water and DMSO, and has strong self-assembly properties.

-Stable targeting performance: cRGD peptide retains high integrin affinity, while HA maintains natural biological activity.

-Suitable for scientific research scenarios: It can be used for multi-directional research such as material synthesis, surface modification, and nanocarrier preparation.

Targeted mechanism of action

The core mechanism of cRGD-PEG-HA is "active targeting+stable carrier". The cRGD peptide segment specifically recognizes α v β 3 and α v β 5 integrins, which are highly expressed in tumor and inflammatory tissues, achieving precise targeted enrichment. PEG segment optimization improves molecular hydrophilicity and dispersibility, reduces particle aggregation, and prolongs material action period. The HA component enhances biocompatibility, reduces material toxicity, and is suitable for interdisciplinary research in biology. Molecules can be embedded into lipid bilayers and grafted onto polymer surfaces to achieve functional modification.

CRGD PEG HA cRGD targeting peptide polyethylene glycol hyaluronic acid

Research application scenarios

1. Synthesis of nanocarriers

As an amphiphilic stabilizer and functional component, prepare liposomes, polymer nanoparticles, and microspheres. Regulating the proportion of molecules to optimize particle size, drug loading capacity, and release performance for drug loading, gene delivery, and catalytic system loading research.

2. Surface modification of materials

Graft onto the surface of polymer and gel materials. Introducing targeted sites to improve biocompatibility, stain resistance, and cell adhesion, for use in biosensors, medical scaffolds, and separation media research.

3. Biological coupling and labeling

As a coupling bridging molecule, functional components such as ligases, antibodies, fluorescent dyes, etc. Constructing targeted probes and detection reagents for biological analysis, target recognition, and in vitro monitoring research.

4. Hydrogel and composite materials

The composite hydrogel was prepared by crosslinking with various polymers. It endows gel with targeting and stimulation responsiveness, and can be used in drug controlled release, tissue engineering scaffold, and flexible biomaterials research.

Carbon Water Technology（Tanshtech）

The company is deeply engaged in the research and development of biological research reagents, and has a platform for synthesis, purification, and characterization. Product line containing phospholipidsPEG、 More than a thousand products, including polysaccharide PEG, targeted peptides, fluorescent markers, etc., support customized synthesis, structural optimization, and mass production. Collaborated with Zhejiang University, Shandong University, South China University of Technology, and others, participated in multiple scientific research projects, and received over a thousand product citations. The technical team provides application solutions, performance testing support, and adapts to the entire scientific research process.

Quality Control and Service

-Strict quality inspection: Multi dimensional detection by HPLC and NMR, purity ≥ 95%, PDI≤1.05。

-Stability guarantee: Dry storage at -20 ℃, stable shelf life.

-Customized services: molecular weight, degree of substitution, and functional groups can be customized as needed.

-Technical support: Provide structural characterization and application reference cases.

The stability and targeting of biomolecules of cRGD-PEG-HA fusion material provide reliable reagents for the interdisciplinary research of nanotechnology, materials science, and biomedicine, and facilitate breakthroughs in cutting-edge scientific research and innovation.