(Mal) 7-8ARM PEG Biotin heterodox eight arm polyethylene glycol

(Mal) 7-8ARM PEG Biotin heterodox eight arm polyethylene glycol

Eight arm polyethylene glycol maleimide (7)/biotin (1)

8arm PEG，1arm-Biotin，7arm-Maleimide

[English nickname 1]8ARM-PEG-Biotin（1）/Mal（7）

[English nickname 2](Mal)7-8ARM-PEG-Biotin

[Structure]

[Brand]Tanshtech (Carbon Water Technology)

PurityOver 95%

[Save]-20℃

Molecular weightPEG:2K,5K,10K,20k

[Other molecular weights]Contact Customer Service

supplementBiotin and Mal The proportion can be customized at any ratio

(Mal) 7-8ARM PEG Biotin heterodox eight arm polyethylene glycol

1. Molecular Overview

(Mal) ₇ -8ARM-PEG Biotin is a functionalized polyethylene glycol derivative with a multi arm star structure. This molecule is composed of an eight armed PEG backbone, with seven arm ends modified with maleimide groups and the other arm containing biotin. This asymmetric end functional design enables it to simultaneously perform multi-point coupling and specific biometric recognition.

2. Reaction activity and functional characteristics

Maleimide groups have high selectivity and rapid reactivity towards thiol groups (- SH), making them suitable for covalent bonding with proteins, peptides, or small molecules containing cysteine.

Biotin groups can form non covalent bonds with Streptavidin or Avidin for molecular recognition, separation and purification, or targeted labeling.

3. Application advantages

The combination of multi-point crosslinking and single point targeting is suitable for constructing multifunctional biomaterials.

The PEG backbone endows it with good water solubility, biocompatibility, and low immunogenicity, making it suitable for both in vivo and in vitro environments.

By controlling the ratio of Maleimide to Biotin (7:1), spatial localization coupling can be achieved, improving the controllability and stability of the constructed system.

4. Typical application areas

Biological coupling and labeling:Used for targeted modification or multi site linkage of proteins, antibodies, enzymes, etc.

Targeted drug delivery:The biotin/streptavidin system is used for targeting, while Maleimide is used for drug conjugation.

Hydrogel crosslinking:Forming a stable three-dimensional network structure under thiol conditions for tissue engineering or drug controlled release.

Construction of biosensors:Biotin achieves surface anchoring, while Maleimide is used for signal molecule modification.

Tanshtech series products

Eight arm polyethylene glycol, seven arm maleimide, and one arm biotin 8arm PEG，1arm-Biotin，7arm-Maleimide

Eight arm polyethylene glycol, seven arm carboxyl, one arm alkynyl 8arm PEG，1arm-Alkyne，7arm-Acetic Acid

Eight arm polyethylene glycol, seven arm azide, and one arm acrylic acid ester 8arm PEG，1arm-Acrylate，7arm-Azide

Eight arm polyethylene glycol, seven arm propylene amide, one arm biotin 8arm PEG，1arm-Biotin，7arm-Acrylamide

Eight arm polyethylene glycol, seven arm amino, one arm maleimide 8arm PEG，1arm-Maleimide，7arm-Amine