Mixing tank_Stainless steel batching tanks_Mixing tank

1、 Overview of the liquid preparation tank

1. A mixing tank, also known as a preparation tank, blending tank, ingredient tank, or mixing tank, is a stainless steel mixing and stirring container that mixes one or several materials according to the process ratio. It is suitable for the preparation and storage of liquid materials in the traditional Chinese medicine, food, and chemical industries. Steam or cold water can be introduced into the jacket to keep the materials at a suitable temperature. It is the preferred equipment for injection, infusion, concentrated and diluted liquid medicine.

There are many types and names of mixing tanks, including stainless steel mixing tanks, magnetic stirring mixing tanks, insulated mixing tanks, buffer mixing tanks, sterile mixing tanks, single-layer mixing tanks, etc. The mixing tank is generally a fully sealed, vertically structured, hygienic and clean container with functions such as heating, cooling, insulation, and stirring. The mixing tank body with heating or cooling function is equipped with a jacket, which can be heated or cooled separately by introducing heating or cooling medium, so that the liquid medicine can be fully dissolved and mixed by the operation of the mixer. The configuration of the liquid distribution tank system mainly includes transmission device, mechanical seal device, temperature control device, spotlight, sight glass, mixing device, manhole feeding port, steam inlet, condensate outlet, material outlet, sewage outlet, sampling port, 360 ° universal cleaning ball. Some also have orifice plate filtration device, weighing and measuring device, liquid level measuring device, circulation device, etc. According to the requirements of the process characteristics, there are single-layer mixing tanks, double-layer insulation mixing tanks, and three-layer heat exchange insulation mixing tanks.

Liquid preparation tank_Stainless steel batching tank_Preparation tank

2. Structural characteristics of stainless steel mixing tank

1. The mixing tank body adopts a hygienic and sterile design, and each pipe mouth is stretched to form a smooth transition, avoiding cleaning dead corners caused by direct socket welding, ensuring the reliability and stability of the production process. Mirror polishing treatment on the surface of the inner tank (roughness Ra ≤ 0.4 µ m);

The outer surface adopts mirror panel or frosted board, which is hygienic and beautiful.

2. The process interface adopts ISO standard quick release chuck type interface, which is hygienic without dead corners, easy to disassemble, and equipped with anti-corrosion gaskets. Ensure service life.

3. Equipped with online cleaning (CIP) and online sterilization (SIP) functions, in compliance with GMP standards.

4. Mechanical stirring or magnetic stirring can be used, and the stirring form is often blade or propeller wheel or anchor type. The specific type of mixing to be used depends on the characteristics of the material.

5. The inner surface is treated with a mirror finish, while the outer surface is matte or has a mirror finish on the upper and lower heads. The straight cylindrical part is matte treated, making it easy to clean and leaving no dead corners.

6. The heating jacket can be of the full jacket type, semi tube type, or honeycomb type. Design jacket forms based on material characteristics and heat transfer requirements to ensure heat transfer efficiency and save costs.

7. Temperature display control system and liquid level display system can be selected as needed. For automatic level requirements, remote output control function can be equipped. For routine operation observation, local display and manual control can be used.

8. The pipe mouth adopts a stretching and flanging process with a curved transition, which is smooth, easy to clean, and has no dead corners, ensuring the reliability, stability, and compliance with GMP requirements of the production process.

9. The equipment seal adopts a special sanitary grade mechanical seal, which is wear-resistant, does not contaminate materials, and has good sealing performance.

3. Parameter selection of the mixing tank:

2、 Overview of Concentrated Mixing Tank

1. Concentrated tank is a tank used for liquid preparation and storage in the pharmaceutical industry. It is a general term in the pharmaceutical industry and is a type of liquid preparation tank. The difference between a concentrated tank and a diluted tank lies in the concentration of the prepared solution. A concentrated solution is diluted and then prepared as a dilute solution. The tank used to prepare high concentration liquids is called a concentrated solution tank, while the tank used to prepare low concentration liquids is called a dilute solution tank. The names used in different industries are different. When used for food preparation and storage, we call it a preparation tank or blending tank, and some are also called a preparation tank or mixing tank. The tank used for preparation and storage in the chemical industry is called a mixing tank or batching bucket. The concentration tank is suitable for the preparation and storage of liquid materials in the traditional Chinese medicine, food, and chemical industries. It can be filled with steam or cold water inside the jacket to keep the materials at a suitable temperature. It is the preferred equipment for injection, infusion, concentration and dilution of medicinal liquids.

Concentrated mixing tanks are generally fully sealed, vertically structured, hygienic and clean containers with functions such as heating, cooling, insulation, and mixing. The concentration tank body with heating or cooling function is equipped with a jacket, which can be heated or cooled separately by introducing heating or cooling medium, so that the liquid medicine can be fully dissolved and mixed by the operation of the mixer. The configuration of the concentrated tank system mainly includes transmission device, mechanical seal device, temperature control device, spotlight, sight glass, mixing device, manhole feeding port, steam inlet, condensate outlet, material outlet, sewage outlet, sampling port, 360 ° universal cleaning ball. Some also have orifice plate filtration device, weighing and measuring device, liquid level measuring device, circulation device, etc. According to the requirements of the process characteristics, there are single-layer concentration tanks, double-layer insulated concentration tanks, and three-layer heat exchange insulated concentration tanks.Liquid preparation tank_Stainless steel batching tank_

Preparation tank

2. Structural characteristics of concentrated mixing tank:

1. The thick mixing tank body adopts a hygienic and sterile design, and each pipe mouth is drawn to form a smooth transition, avoiding cleaning dead corners caused by direct socket welding, ensuring the reliability and stability of the production process. Mirror polishing treatment on the surface of the inner tank (roughness Ra ≤ 0.4 µ m);

The outer surface adopts mirror panel or frosted board, which is hygienic and beautiful.

2. The process interface adopts ISO standard quick release chuck type interface, which is hygienic without dead corners, easy to disassemble, and equipped with anti-corrosion gaskets. Ensure service life.

3. Equipped with online cleaning (CIP) and online sterilization (SIP) functions, in compliance with GMP standards.

4. Mechanical stirring or magnetic stirring can be used, and the stirring form is often blade or propeller wheel or anchor type. The specific type of mixing to be used depends on the characteristics of the material.

5. The inner surface is treated with a mirror finish, while the outer surface is matte or has a mirror finish on the upper and lower heads. The straight cylindrical part is matte treated, making it easy to clean and leaving no dead corners.

6. The heating jacket can be of the full jacket type, semi tube type, or honeycomb type. Design jacket forms based on material characteristics and heat transfer requirements to ensure heat transfer efficiency and save costs.

7. Temperature display control system and liquid level display system can be selected as needed. For automatic level requirements, remote output control function can be equipped. For routine operation observation, local display and manual control can be used.

8. The pipe mouth adopts a stretching and flanging process with a curved transition, which is smooth, easy to clean, and has no dead corners, ensuring the reliability, stability, and compliance with GMP requirements of the production process.

9. The equipment seal adopts a special sanitary grade mechanical seal, which is wear-resistant, does not contaminate materials, and has good sealing performance.

3. Parameter selection of concentrated mixing tank:

3、 Diluted tank

1. Overview of Dilution Tank Dilution tank is used for concentrated/diluted solutions in the pharmaceutical industry. The tank body is equipped with a jacket, which can be heated, cooled, and kept at a constant temperature. Compared to the concentrated mixing tank, the mixing power of the dilute mixing tank is smaller for the same model. A dilution tank is generally a fully sealed, vertically structured, hygienic and clean container with functions such as heating, cooling, insulation, and mixing. The dilution tank body with heating or cooling function is equipped with a jacket, which can be heated or cooled separately by introducing heating or cooling medium, so that the liquid medicine can be fully dissolved and mixed by the operation of the mixer. The configuration of the dilution tank system mainly includes transmission device, mechanical seal device, temperature control device, spotlight, sight glass, mixing device, manhole feeding port, steam inlet, condensate outlet, material outlet, sewage outlet, sampling port, 360 ° universal cleaning ball. Some also have orifice plate filtration device, weighing and measuring device, liquid level measuring device, circulation device, etc. According to the requirements of the process characteristics, there are single-layer dilution tanks, double-layer insulated dilution tanks, and three-layer heat exchange insulated dilution tanks.

2. Structural characteristics of dilution tank:

1. The dilution tank body adopts a hygienic and sterile design, and each pipe mouth is drawn to form a smooth transition, avoiding cleaning dead corners caused by direct socket welding, ensuring the reliability and stability of the production process. Mirror polishing treatment on the surface of the inner tank (roughness Ra ≤ 0.4 µ m);

The outer surface adopts mirror panel or frosted board, which is hygienic and beautiful.

2. The process interface adopts ISO standard quick release chuck type interface, which is hygienic without dead corners, easy to disassemble, and equipped with anti-corrosion gaskets. Ensure service life.

3. Equipped with online cleaning (CIP) and online sterilization (SIP) functions, in compliance with GMP standards.

4. Mechanical stirring or magnetic stirring can be used, and the stirring form is often blade or propeller wheel or anchor type. The specific type of mixing to be used depends on the characteristics of the material.

5. The inner surface is treated with a mirror finish, while the outer surface is matte or has a mirror finish on the upper and lower heads. The straight cylindrical part is matte treated, making it easy to clean and leaving no dead corners.

6. The heating jacket can be of the full jacket type, semi tube type, or honeycomb type. Design jacket forms based on material characteristics and heat transfer requirements to ensure heat transfer efficiency and save costs.

7. Temperature display control system and liquid level display system can be selected as needed. For automatic level requirements, remote output control function can be equipped. For routine operation observation, local display and manual control can be used.

8. The pipe mouth adopts a stretching and flanging process with a curved transition, which is smooth, easy to clean, and has no dead corners, ensuring the reliability, stability, and compliance with GMP requirements of the production process.

9. The equipment seal adopts a special sanitary grade mechanical seal, which is wear-resistant, does not contaminate materials, and has good sealing performance.

4、 Comparison relationship between dilution tank and concentration tank

1. Definition of dilution tank and concentration tank:

Dilute mixing tank and concentrated mixing tank are mixing and stirring containers that mix one or several materials according to the process ratio. The concentrated mixing tank is opposite to the dilute mixing tank, with the same function, slightly different processes, and slightly different equipment parameters.

2. Application of dilute and concentrated mixing tanks:

Dilute and concentrated mixing tanks are mainly used in industries such as dairy products, food, beverages, pharmaceuticals, and pharmaceuticals, and are most commonly used in the pharmaceutical and dairy industries.

3. Overview of dilution tanks and concentration tanks:

The design of the dilution and concentration tanks produced by Beijing Rena is reasonable, the process is advanced, and fully meets the requirements of national GMP certification. Dilute and concentrated tanks often adopt a vertical structure with finely polished inner liners. The mixing of the inner cylinder of the dilute and concentrated mixing tanks includes frame type, anchor type, push type, blade type, etc., and the outer insulation is filled with polyurethane material for insulation. The exterior is insulated with mirror panels or frosted boards, and the tank has consistent gloss. All parts of the dilution tank and concentration tank that come into contact with the liquid medicine are made of 316L material, while the rest are made of 304 material. The bottom head of the inner tank is an elliptical head, and the top of the tank is equipped with a feeding port, a reflux port, a disinfection port, a cleaning ball, a manhole, a breathing port (0.22um air respirator), and a stirring system. The bottom of the tank is equipped with a condensate outlet, discharge outlet, sewage outlet, sampling outlet, temperature probe, and liquid level sensor.

4. Functions of dilution tank and concentration tank:

Dilute and concentrated mixing tanks have heating, cooling, insulation, and stirring functions. The tank body is designed with process pipe openings such as material inlet, pure water outlet, discharge outlet, and sampling outlet, which can provide conditions for the liquid mixing process. After the liquid preparation is completed, the direct steam can be turned on to achieve sterilization and disinfection function. After the high-temperature liquid preparation process is completed, if cooling is required, the discharge valve can be opened for discharge after cooling. In addition, pharmaceutical dilution tanks and concentration tanks generally have sterilization functions.