The PEEK hand tight fitting for liquid chromatography is a key component commonly used in high-performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UPLC) systems, made of polyetheretherketone (PEEK) material. Liquid phase PEEK joints have become an ideal choice for modern chromatographic systems due to their chemical inertness, pressure resistance, and ease of use, especially suitable for biological analysis and corrosive mobile phase conditions. Proper selection (inner diameter, pressure) and installation are key to ensuring system performance.
Liquid chromatography PEEK hand tight joint
Liquid chromatography PEEK hand tight jointisThe key components commonly used in high-performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UPLC) systems are made of polyetheretherketone (PEEK) material. Liquid phase PEEK joints have become an ideal choice for modern chromatographic systems due to their chemical inertness, pressure resistance, and ease of use, especially suitable for biological analysis and corrosive mobile phase conditions. Proper selection (inner diameter, pressure) and installation are key to ensuring system performance.
Material characteristics:
PEEK (polyetheretherketone): a high-performance engineering plastic with the following advantages:
◆ Corrosion resistance: Resistant to most organic solvents, acids, and bases (but not to strong oxidizing acids such as concentrated sulfuric acid and nitric acid).
◆ High pressure resistance: capable of withstanding pressures up to 0 MPa (approximately 6000 psi), suitable for HPLC systems.
◆ Biological inertness: does not contaminate the sample, suitable for the field of biomedicine.
Flexibility: easier to install than metal joints, reducing the risk of liquid leakage.
Main types:
◆ Standard PEEK connector:
Used for routine liquid phase analysis, connecting chromatography columns, pipelines, or detectors.
Common interface specifications: 1/16 inch (outer diameter), compatible with common HPLC tubing.
◆ PEEK hand tight joint:
No tools required, manually tighten to seal, convenient and quick replacement.
Suitable for scenarios with frequent disassembly (such as method development).
Key parameters:
Inner diameter (ID): commonly 0.1 mm, 0.13 mm, 0.25 mm, etc., affecting the dead volume of the system.
Pressure limit: usually 15-40 MPa, to be selected according to the system pressure.
Temperature range: generally -10 ° C to+100 ° C (special models are required for high-temperature applications).
Application Scenario:
Biochromatography: Avoid interference from metal ions (such as protein and nucleic acid analysis).
Ion chromatography (IC): resistant to acid and alkali corrosion.
Conventional HPLC/UPLC: Connect chromatography columns, injection valves, detectors, etc.
Precautions for use:
Avoid strong oxidants such as concentrated nitric acid and chromic acid, which may damage PEEK.
Pressure limit: Overpressure may cause joint rupture.
Correct installation: Ensure that the threads are aligned to avoid deformation caused by excessive tightening.
Regular inspection: Aging or worn joints may leak fluid.
