Fully automatic sampling and dissolution system

The Huarong DS-1206AT fully automatic sampling and dissolution system, combined with a 12 cup dissolution device and an automatic sampler, achieves fully automatic drug administration, dissolution, sampling, and fluid replenishment, meeting the requirements of the Chinese Pharmacopoeia and the United States Pharmacopoeia. The main features include coaxial design, precise temperature control ( 0.5 ℃), automatic center positioning, automatic lifting, dual drive shaft system, automatic synchronous dosing, online secondary filtering, precise mechanical verification, * user management and audit tracking, paperless report management, and remote system upgrade. Engineers stationed in multiple regions across the country provide efficient support.

Product Introduction

HuarongDS-1206ATFully automatic sampling and dissolution system, by12Composed of a cup dissolution device and an automatic sampler. The instrument adopts a fully automatic control system to achieve integrated operations such as automatic dosing, dissolution, sampling, and fluid replacement of drugs, achieving precise temperature control, precise sampling, automatic fluid replacement, and automatic cleaning. It elevates conventional dissolution technology to a higher level and is highly favored by users. The specific technical features are as follows:

Key Features:

1. Compliant with regulatory requirements

HuarongDS-1206ATFully automatic sampling and dissolution systemThe performance meets the requirements of domestic and foreign regulations and standards such as the Chinese Pharmacopoeia, the United States Pharmacopoeia, and the Guidelines for Mechanical Validation of Drug Dissolution Testers.

2. oar/Basket coaxial methoddesign

①Paddle basket coaxialDesign, the same host can perform paddle, basket, and drum methodsPaddle disc methodThe small cup method,Immersion pool methodSwitching;

②Add a sealing ring at the coaxial connection to ensure a tighter connection and long-term operation of the shaft without looseness;

③A common transmission system that can connect interchangeable baskets, blades, and small blades. After the initial positioning of the height, there is no need to readjust, making switching extremely convenientCombining highPrecision machining technology ensures the swing degree of the shaft≤±0.2mm.

3. Precise Temperature Control

The instrument is equipped with a handheld high-precision electronic temperature probe, which is flexible and convenient for monitoring the temperature of each dissolution cup medium, ensuring accurate temperature control≤±0.5℃.

4.Automatic center positioning dissolution cup

①Integrated dissolution cup, automatic center positioning and orientation, automatic locking, high precisionCan try as much as possibleReduce variability between positions while improving uniformityoneSex.

②Unloading1000Secondary dissolutionCup centralitychange≤0.3mm.

5.Automatic lifting system

①The automatic lifting platform keeps the machine head in a horizontal state for a long time, ensuring the verticality and coaxiality of the dissolution analyzer shaftLong term degreeunchanged;

②autonomousDesign to ensure the continuous stability of drug dissolution experiments and reduce the risk of drug dissolution differences caused by changes in instrument mechanical properties;

③The top of the shaft of the dissolution tester is fixed with a double bearing design, ensuring that the shaft is always in a vertical coaxial state during long-term operation, ensuring the stability of the experiment and achieving industry level coaxiality.

6.Dual drive design of shaft system

①12Channel division6+6twoZone control can achieve dual solvent and dual speed dissolution experiments, with speed errors≤±0.3rpm；

②Users can freely choose according to their preferences6Cup or12Cup dissolution experiment;

③The sampler adopts6+6Dual group design allows for free grouping sampling, with sampling time that can be freely set for each group without interfering with each other, meeting the requirements of different experimental conditions;

④12Channel independent pipeline system, precise sampling, precise fluid replenishment, ensuring the accuracy of the experiment.

7. Automatic synchronous dosing device

①oneThe automatic administration of tablets, capsules, and granules can achieve automatic and manual synchronous administration.

②Quick detachable drug deliveryDevice design, just need30In seconds, the medication dispenser can be removed for cleaning to avoid drug residue.

8. Online secondary filtering

①Manual or automatic replacement of filters, excellent flow path design ensures full adsorption of filters;

②canCooperate with oneselfReplacing the membrane and filter is more convenient;

③Sampling into liquid vials, efficient and time-saving;

④Can be connected to the market for sale0.45μmFilter, the sample can be taken without further filteringHPLC.

9. Precision Mechanical Verification System

①Huarong260-DSThe mechanical certification system consists of various mathematical testing instruments that have been verified by third-party metrologyCombined with Huarong Instrument260-DSComposition of workstation software;

②260-DSMechanical certification systems can bring higher analysis accuracy and efficiency to customers. At the same time, customers are free to increase the frequency of authentication to achieve higher integrity;

③260-DSThe mechanical certification system is compatible with all open dissolution testers, including convenient fixed buckles and adjustment capabilities for dissolution cups of different specifications;

④After installation in placeUsing Bluetooth communicationReal time transmission of data from detection instruments to the computer version260-DSWorkstation software, where the quantitative values of each parameter are recorded and displayed in real-time through the software;

⑤can provide3QVerification service（IQTheOQThePQ）.

10. *The User Management System

①Can store all records and experimental reports;

②Allocated at least3Permission levels: system administrator, supervisor, operator;

③Can be preset1000A login account;

④Can establish user groups and set group member permissions;

⑤Customers can customize role permissions based on their own risk assessment;

⑥Can connect to enterprise servers and synchronize enterprise office domain accounts.

11. Equipped with audit tracking function

①Login records, operation records, experiment records, and system anomaly reports automatically generate accurate and consistent electronic data. All electronic data is protected and cannotcompileChange or delete;

②Large data storage capacity, capable of storing approximately25000Batch experiment report.

③can pass throughUDrive or connect to enterprise servers for real-time backup, allowing remote login to the enterprise server to view and print all records and experimental reports.

12. paperlessChemical reportManagement

The instrument can be connected to a network printer and stored locally on the machineUSearch and print disks, enterprise servers, etc. according to experimental requirements.

13. Remote upgrade of operating system

Huarong InstrumentSupporting remote system upgrades, we can provide free remote system upgrade services for instruments according to customer needs, saving time and manpower, and providing customers with a more friendly and convenient interface operation experience.

14. Complete technical service system

①Technical Support Huarong provides customers with fast and effective personal support through telephone, email, remote access, and on-site maintenance. Huarong operates nationwide20Multiple major cities have engineer stations to provide fast and efficient localized services;

②Spare parts service: Establish a spare parts warehouse, sign spare parts service agreements with key suppliers, shorten procurement cycles, and ensure the continuity of spare parts supply;

③Annual maintenance: Every year1-2Deep maintenance of the secondary system to eliminate hidden dangers;

④System upgrade: Assist customers in remotely upgrading and optimizing their existing systems;

⑤Verification: Arrange engineers to be stationed on site to comprehensively address customer emergency needs.