EcoChem Traditional Chinese Medicine Element Enrichment Analysis System

EcoChemEnrichment Analysis System for Traditional Chinese Medicine Elements

Guizhi, Codonopsis pilosula, and Scutellaria baicalensis are commonly used traditional Chinese medicinal herbs in China. Now we need to understand the distribution of various elements inside these Chinese medicinal materials, in order to gain a better understanding of the enrichment of each element, and to explore the relationship between elements and the quality and efficacy of Chinese medicinal materials, as well as the enrichment of heavy metal pollution in the future.

Laser induced breakdown spectroscopy in recent years（LIBS）Technology, as an emerging element detection and analysis technique, has been widely applied in many fields such as ecological sample measurement, germplasm resource identification, jewelry, geology, and industry. When the laser acts on the surface of the sample, it induces the generation of plasma containing information about the sample material in a very short period of time. By collecting and analyzing the spectra emitted by plasma, establish a one-to-one correspondence between spectra and elements. This can detect most of the elements in the periodic table, with a detection limit of up toppmGrade. After calibration with standard substances, the content information of elements can be further obtained.

Taking cassia twigs as an example, scan the surface element distribution of cassia twig samples. In order to obtain better signals during the experiment, we used0.35MsTo delay the time,80Energy output, light spot100Mm，5The signal accumulation of sub pulses. Through element distribution analysis, the distribution results of each major element were obtained in one go, as shown in the following figure. Warm colors indicate high element content, while cool colors indicate low element content.

among which,CaTheNa，MgThe elements are mainly enriched in the outer layer, with very low content in the core.KThe elements are mainly enriched in the outer layer, and there is also a certain amount in the core,KThe element core content is relatively high.CThe distribution of elements is uneven, mainly enriched in the left half of the sample.

Through this experiment, we conducted in situ analysis of the element distribution in cinnamon branches and understood the distribution of different elements in cinnamon branches. We can further analyze the elemental distribution of other traditional Chinese medicinal materials, and even measure them together with trace elements in soil to understand the relationship between the elemental content and distribution of trace elements in soil and traditional Chinese medicinal materials. To better understand the pharmacological properties of traditional Chinese medicine and improve its quality.

EcoChem Traditional Chinese Medicine Element Enrichment Analysis SystemMain technical indicators:

Laser system:

Laser energy:200mJ@1064nmEnergy output0-100%Adjustable; （25mJ@266nmLaser optional)

Spot quality control system

Reproducibility: 20Hz, pulse width<6ns, DI water cooling system

Spot size:50300 μ m continuously adjustable

Laser shutter: automatic dual shutter, stable control of laser energy and LIBS signal

Laser safety: Level I, equipped with laser locking protection device

Detector: The spectral width can cover the measurement range of all elements, and can measure the information of all elements in the periodic table such as C, P, Mg, Si, Fe, Ca, Na, K, N, H, O, etc. The spectral wavelength accuracy is ± 0.08nm; Spectral resolution of 0.10nm @ 400nm; The door delay time is 0.5ns-1ms.

Equipped with automatic height adjustment function

workbench:

Fully automatic XYZ stroke, XY stroke 100mm × 100mm, Z stroke50mm， Speed 0-10mm/s

XY stroke resolution: 0.2 μ m, Z stroke resolution: 1 μ m

The sample chamber can be filled with helium or argon gas

operating software

Chinese software interface, including NIST and ElementLIBS element recognition databases. It is easy to detect and identify elements on the periodic table and label them with information. The software also has the following functions: the software can perform command operations on all hardware components (laser, spectrometer, 3D workbench, gas path, etc.), with a friendly interface, intuitive operation, and simple use; Built in multiple sampling methods, including single point, multi-point, straight line, matrix point, etc; Equipped with automatic focus control, it can quickly and conveniently identify samples; Can control the dual lenses (panoramic view and magnifying view) built into the system; Built in PLS, PCR and other calibration calculation models can quickly calculate element content; Built in PCA, HCA and other computational models for element classification analysis and traceability; Can perform element mapping analysis; Accurate control of the gas path; Built in conversion of various data formats such as txt, dat, etc; Built in multiple common soil and plant standard curve libraries in China, convenient for users to refer to and call.

Data Processing Center:

Dedicated quad core CPU, 16GB memory desktop computer, and 27’monitor

Optional accessories:

Desktop tablet press, helium or argon gas