Canadian Personal Molecular Interaction Analyzer OpenSPR

Canadian Personal Molecular Interaction Analyzer OpenSPR

Nicoya was founded in Canada in 2012. In early 2015, Nicoya officially launched the new generation of high-performance personal molecular interaction analyzer OpenSPR. As of 2021, Nicoya has more than 100 employees, covering over 40 countries, serving more than 600 installed customers, and publishing over 130 articles. In 2021, Nicoya launched the fully automatic high-throughput molecular interaction analyzer Alto, which integrates digital microfluidic technology.

Nicoya's mission is to help scientists successfully improve human life. Human beings will always be troubled by diseases such as cancer, Alzheimer's disease, etc. *Millions of researchers are tirelessly studying these diseases, and we provide services to these scientists.

Introduction to OpenSPR

Introduction to Personal Molecular Interaction Analyzer OpenSPR

OpenSPR is a desktop surface plasmon resonance (SPR) instrument that provides high-quality, label free interaction analysis results. The local surface plasmon resonance (LSPR) technology based on nanostructured sensors used in OpenSPR has higher repeatability and sensitivity in affinity data.

OpenSPR has assisted clients in publishing over 130 high-level articles in international journals, with an installed capacity of over 600 and an installed capacity of over 70 in China. It has received high praise from a large number of researchers and provides efficient and convenient research tools for scientific research in fields such as life sciences, drug research, and cancer medicine in China!

Product advantages

Desktop style

Compact and portable overall structure, with more flexible usage scenarios

■ Quick to get started

Guided software, easy to operate, low entry threshold, anyone can conduct SPR experiments

■ High performance

Higher sensitivity, lower solvent effect, smaller temperature impact, suitable for coarse samples and nanoparticles, etc

Low cost

Has significant low-cost advantages in instrument purchase, consumables usage, and post maintenance

Application method

Dynamics/affinity, binding analysis, competitive experiments, target recognition, epitope mapping, concentration analysis

Applicable samples

Proteins, liposomes, carbohydrates, antibodies, nucleic acids, small molecules, cells, viruses, nanoparticles, etc

Application field

Immunological research, pharmacological testing, forensic identification, agricultural pollution detection, food safety testing, marine biology research, nanomaterials, etc

AIto Introduction

Fully automatic high-throughput molecular interaction analyzer Alto

Nicoya's Alto integrates digital microfluidics (DMF) and nanotechnology, providing high-quality, label free intermolecular interaction detection data suitable for crude sample extraction without maintenance. DMF technology can accurately control 0.35uL droplets, so only 2uL of sample is needed to complete one round of affinity experiments.

The hardware and software used by Alto have high throughput, achieving end-to-end automation of experiments and can run continuously 24 hours * 7 days.

Alto features a flexible 16 channel design and intuitive data analysis platform, making it convenient for users to use and optimize the experimental process in real-time.

Alto product advantages

Data quality

-High detection accuracy, low noise and diffusion

-Mixing time<0.1s, weak mixing

High throughput supported by DMF

-16 channels * 64 analytes, one experiment can obtain>1000 sets of kinetic and affinity data

-24-hour * 7-day continuous operation, with no downtime between experiments, saving time and costs.

Low sample demand

-Obtaining a set of affinity data only requires 2ul of sample, which is 500 times lower than traditional SPR

-Disposable card box, suitable for rough sample extraction

■ Operation and maintenance

-Automatic gradient dilution, DMF technology controls samples for precise automated gradient dilution

-Guided software operation, automatic error prompts, and optimization guidance to reduce learning and usage difficulty

-No need for cleaning, no blockage, no leakage; Low possibility of mechanical failure

Canadian Personal Molecular Interaction Analyzer OpenSPR