β 2-microglobulin

Product Name:β 2-microglobulin

Specification: See product label

Concentration:2.0mg/ml

Storage conditions:-20℃

Background introduction (for reference only):

B2Microsphere protein(BMG;B2-MG)fromB2MGenetic coding. It is located on the surface of the cell in the alpha region3Beside the chain. With alpha3Different, β2There is no transmembrane area. In β2Directly above (i.e. further away from the cell) is alpha1Chain itself is in alpha2Next to it. β2Microglobulin is not only associated withMHC IThe alpha chain of the class molecule binds, and also interacts withIClass molecules such asCD1TheMR1, andQa-1Binding (a form of heterologous antigen). Another function of it is to work withHFEProteins are associated and jointly regulate the expression of hemoglobin in the liver. Hemoglobin targets iron transporters on the basement membrane of intestinal cells and the membrane of macrophagesferroportinDegradation leads to a decrease in iron intake from food and a decrease in iron intake fromMPSThe iron released by the recovered red blood cells in the mononuclear phagocytic cell system is reduced. The loss of this function can lead to iron overload and hemochromatosis.

Usage:

Balance with room temperature and shake well before use. It can be divided and diluted according to specific requirements. Please seal and store the remaining products as soon as possible after use to avoid product contamination, evaporation, dilution, etc. If multiple uses are required, please pack and store according to the dosage to avoid repeated freezing and thawing.

Notes:

1.This product is only used for scientific research experiments. During operation, it is necessary to handle clinical specimens and take corresponding experimental protective measures

2.When operating, please wear laboratory clothes, protective masks, and disposable laboratory gloves. Direct contact with hands or other parts of the body is strictly prohibited. The product contains preservatives, which are harmful to ingestion and must not be consumed.

3.This product is strictly prohibited from being used for medical diagnosis, consumption, cosmetics, and other purposes.

4.Please seal and store the remaining products as soon as possible after use to avoid product contamination, evaporation, etc; Long term storage is required. Please pack and store according to the dosage in a timely manner to avoid repeated freezing and thawing.

5.After use, please dispose of the waste products according to the laboratory's relevant waste regulations and do not dispose of them at will.

6.Please use before the expiration date of the product.