Definition and processing level

• EO sterilizationUsing ethylene oxide gas to disrupt the DNA, RNA, and protein structures of microorganisms through alkylation reactions,Kill all microorganisms, including bacterial spores, to achieve a sterile level (SAL ≤ 10 ⁻⁶).
  
• EO disinfectionSame use of ethylene oxide gas, but only needs to kill most pathogenic microorganisms, reduce pollution risk, and does not requireAseptic, suitable for scenarios with low requirements for microbial control.
  
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Applicable subjects

• EO sterilizationMainly used for high-risk medical devices such as surgical implants, catheters, and precision instruments that are not resistant to high temperatures or humidity.
  
• EO disinfectionSuitable for medium to low-risk items, such as some laboratory equipment, or as a pre-treatment step before sterilization.
  
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operating procedure

• EO sterilization process: Preprocessing (temperature and humidity regulation) →EO gas permeation (concentration 300-1200mg/L) →Sterilization stage (lasting for several hours) →Ventilation analysis (removal of residual EO).
  
• EO disinfection processThe parameter requirements are lower than sterilization (such as shortening the action time or reducing the concentration), and ventilation is still required after the end, but the process is relatively simplified.
  
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Safety and residual

• EO gas has moderate toxicity and can be absorbed through the respiratory tract and skin. Long term exposure may cause cellular abnormalities or cancer, and it is highly irritating.
  
• Different products have strict requirements for the residual amount of EO, for example, disposable medical supplies generally do not exceed 10 μ g/g, and special products such as packaging require no more than 5 μ g/g.
  
• After EO sterilization, analysis treatment (heating or natural analysis) is required to reduce residue and ensure safety.
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summary