Ultrasonic atomizer used for biosensors

Ultrasonic atomizer used for biosensors

Biosensors,It is an instrument that is sensitive to biological substances and converts their concentrations into electrical signals for detection. Biosensitive materials generally include enzymes, antibodies, antigens, microorganisms, cells, tissues, nucleic acids, and other bioactive substances. Common biosensors include blood glucose meter, pregnancy test paper, COVID-19 antigen test paper, etc.

Ultrasonic atomizer used for biosensorsDue to its uniformity, high material utilization rate, and friendliness towards fragile substrates, it plays a key role in the preparation of "membranes" for biosensors. Simply put, ultrasonic spraying technology is mainly used to accurately, thinly, and uniformly coat various "functional materials" of biosensors onto the electrodes or functional areas of the sensors,Forming a coating film.

Advantages and characteristics:

Compared with traditional spraying (such as air pressure spraying) or adhesive and spin coating,Ultrasonic sprayingIt has unique advantages in the manufacturing of biosensors and has become a hot topic in current research and industrialization:

1. Ultra high uniformity:It can generate droplets with good monodispersity, forming a uniform coating thickness, ensuring consistent sensor performance, small intra batch and inter batch differences, and improving product yield and reliability.

2. Extremely low atomization pressure:Atomization relies on acoustic energy rather than high-pressure gas. Protect the activity and structure of fragile biomolecules, such as enzymes and antibodies, to prevent deactivation due to shear forces.

3.higherMaterial utilization rate:The spraying mode is controllable, with very little overspray. Save expensive biological reagents and nanomaterials (such as gold nanoparticles and carbon nanotubes), significantly reducing production costs.

4. Accurate thickness control:By adjusting the flow rate, nozzle speed, etc., the film thickness can be precisely controlled (from nanometer to micrometer level). Optimizing sensor response, film thickness directly affects sensitivity, response time, and linear range.

5. Suitable for complex substrates:Can be sprayed on flat, curved, and even porous materials. Expand the possibilities of sensor design, such as flexible electrodes and channel coatings within microfluidic chips.

6. No blockage:The atomization process is mild and friendly to suspensions containing particles, such as nanomaterial ink. Suitable for spraying conductive ink, enzyme nanoparticle composite materials, etc.

Ultrasonic precision spraying technology provides a high-precision, high-efficiency, and cost-effective thin film deposition solution for the manufacturing of biosensors. It directly enhances the sensitivity, repeatability, and stability of biosensors by implementing ultra-thin, uniform, and controllable bioactive films, and is one of the key enabling technologies for driving the next generation of high-performance, wearable, disposable biosensors from the laboratory to industrial large-scale production.