Tissue engineering cartilage bioreactor

The dynamic static pressure environment plays an important role in the cultivation of chondrocytes. When constructing tissue-engineered cartilage by combining chondrocytes with biodegradable materials, static culture is usually used, which leads to defects such as hollowing in the cartilage tissue constructed in vitro. Its mechanical properties are far inferior to normal cartilage and cannot meet the requirements of clinical transplantation. Currently, the reported static pressure environment is not in a closed environment, and it is difficult to achieve a dynamic static pressure cultivation environment, resulting in many defects such as limited cultivation time.Tissue engineering cartilage bioreactorIt can simulate a dynamic static pressure environment of cartilage mechanics in the body, provide a way to apply static pressure stress of different frequencies and sizes, and dynamically construct human cartilage tissue. It can adjust the frequency, magnitude, and flow condition of static pressure, and can simultaneously cultivate multiple cartilage tissues. It adopts fully sealed culture to avoid contamination during chondrocyte culture.

1Tissue engineering cartilage bioreactorMain functions:

(1) Can create a static pressure perfusion culture environment;

(2) Can cultivate tissue-engineered cartilage tissue, human ear cartilage, cartilage slices, etc;

(3) Adopting modular structural design;

(4) Capable of collecting data and conducting mechanical analysis on various cultivation parameters.

2. Technical parameters:

(1) Static pressure range: 1-0.4MPa;

(2) Irrigation flow rate: 0-20ml/min, adjustable irrigation flow rate;

(3) Frequency control range: 0-10Hz;

(4) Power supply voltage: AC220V ± 10%/50Hz ± 2%;

(5) Output power: 100W;

(6) Dimensions (mm): 450 × 450 × 500;

(7) Number of cultivation: 1.

3. This product has been granted a national invention patent authorization:patentNumber: ZL201510760414.9.

4. After sales service and training:

(1) Free delivery to the user's address, free on-site installation and debugging. From the day the installation and debugging pass the user's acceptance, the quality guarantee period is 1 year, and full maintenance is free during the quality guarantee period.

(2) During on-site installation and debugging, technical personnel are responsible for training the operators. The number of trainees is not limited until the users can independently use and maintain the equipment.

(3) Repair response time ≤ 2 hours, proposed solution ≤ 24 hours, on-site technical support ≤ 48 hours.