Tensile viscometer

Tensile viscometerIntroduction:

Viscosity is an important parameter for biomacromolecule drugs such as protein/antibody preparations. Fluids are divided into Newtonian fluids and non Newtonian fluids. For Newtonian fluids, viscosity values are only related to temperature and not to shear rate; The viscosity value of non Newtonian fluids is not only related to temperature, but also to shear rate. Different viscosity behaviors may occur at different shear rates, and high concentrations of biological agents are typical non Newtonian fluids.

Why chooseTensile viscometer？

Before 2015, the United States Pharmacopeia included four viscosity measurement methods, numbered 9119129131911. Due to 911 being a capillary viscometer, 912 being a rotary viscometer, and 913 being a drop ball viscometer, which cannot accurately set the shear rate, they are only suitable for measuring Newtonian fluids. The rotational rheometer belongs to macroscopic rheometer counting. Although it can set the shear rate and is suitable for measuring non Newtonian fluids, the rotational rheometer requires rich operating experience, a large amount of samples, a limited range of shear rates, insufficient mechanical resolution for low viscosity samples, and is not a closed system, making it unsuitable for air sensitive and volatile samples; There are significant challenges in measuring the viscosity of biological agents and complex fluids.

Therefore, in the 2015 edition of the United States Pharmacopeia, on the basis of the first four viscosity measurement methods, a fifth viscosity measurement method, the 914 method, was added. This method can set different shear rates and accurately and quickly measure the true viscosity of Newtonian fluids and non Newtonian fluids with only a small amount of samples. The results have high repeatability and can recover samples. Therefore, the USP914 method is particularly suitable for the development of biological agents and viscosity measurement.

VROC technology is a measurement method that meets the requirements of the United States Pharmacopeia USP914. USP914 adopts Rheosense's V (viscometer) R (Rheometer) O (On) C (Chip) chip viscosity rheological integration technology. Regardless of the instrument structure, measurement principle, measurement process, calculation and calibration, only the VROC chip method meets the requirements of USP914 method.

Economically affordable, it can quickly measure samples from anywhere as small as 100 μ L. With rechargeable batteries and a weight of less than 1 kilogram, it takes less than 1 minute to measure, allowing us to measure anytime and anywhere in different locations. Used in conjunction with a chip cleaning workstation, one click cleaning of chips ensures stable and reliable measurements.

Technical parameters:

Minimum sample volume: 100 μ L

Work without supporting software

Characterization of Newtonian and Non Newtonian Fluids

Shear rate range (1/s): 1.7~5800

Wide viscosity range: 0.2~20000 mPa-s (or cP)

Temperature range: 18 ° C-50 ° C*

Accuracy: up to 2% of the reading

Repeatable measurement up to 0.5% of the reading