Recombinant human brain-derived neurotrophic factor

BDNFPromote the survival, growth, and differentiation of neurons. It is the main regulatory factor for synaptic transmission in numerous regions of the central nervous system.BDNFChanges in expression occur in neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.All neurotrophic factors have six conserved cysteine residues that form three disulfide bonds, and all have approximately at the amino acid level50%The consistency of the sequence.

It is widely distributed in the central nervous system and plays an important role in the survival, differentiation, growth and development of neurons during the development of the central nervous system. It can prevent neuronal damage and death, improve the pathological state of neurons, promote the regeneration and differentiation of damaged neurons, and other biological effects. It is also necessary for mature neurons in the central and peripheral nervous systems to maintain survival and normal physiological functions.