Recombinant human GDPD5 protein

1、 Product information:

Product Name: RecombinatorGDPD5protein

Product Specifications10ug，50ug

Storage temperature:-20Freezing at ℃

Validity period:12month

Source: Escherichia coli

Molecular weight:13kDa

amino acid:1-127aa

Full name:glycerophosphodiester phosphodiesterase domain containing 5

labelN/CEnd with6×Hislabel

Purification method:NI-NTAAffinity purification

Purity: ≥85% (throughSDS-PAGEdetermination)

Concentration:1mg/ml (throughSDS-PAGEdetermination)

Endotoxin: not detected

Biological activity: undetected

2、 Usage:

The redissolved protein solution can be diluted with distilled water. Please pack separately to avoid repeated freezing and thawing.

3、 Product background (for reference only):

GDPD5, full name is glycerol phosphodiesterase domain protein5（glycerophosphodiester phosphodiesterase domain containing 5）, also known asGDE2It belongs to the glycerol phosphodiesterase family. As a versatile enzyme,GDPD5Plays a crucial role in regulating cellular metabolism and differentiation. Research has shown that it can hydrolyze deacetylated glycerophospholipids, participate in regulating intracellular osmotic pressure balance and bile alkali metabolism. In the nervous system,GDPD5/GDE2It is crucial for the normal differentiation of spinal motor neurons and the growth of neuronal processes induced by retinoic acid. In addition, this protein is also closely related to the occurrence and development of cancer. Its abnormal expression has been observed in many cancers, such as breast cancer, colorectal cancer, and can affect the invasiveness, metastasis, and chemotherapeutic sensitivity of tumor cells. Research has confirmed that inhibitionGDPD5It can change the metabolism spectrum of bile base phospholipids of breast cancer cells from high to lowmalignancyFeature turning lowmalignancyCharacteristics, therefore considered as potential cancer treatment targets.

4、 Attention:

1. The product is only for scientific research experiments and should not be used for other purposes such as food, cosmetics, clinical medicine, etc. During use, it is necessary to handle clinical specimens and take corresponding protective measures.

2. When using, please wear laboratory clothes, protective masks, laboratory gloves, etc., take good experimental protection, and avoid direct contact.

3. Do not dispose of the remaining products at will. Please follow the relevant regulations for the disposal of chemical waste.

4. Please use the product before its expiration date.

Recombinant humanGDPD5protein