Pilot/Commercial Nanodrug Continuous Preparation System (GMP)

NegotiableUpdate on 05/06

Model

Nature of the Manufacturer: Producers

Product Category

Place of Origin

Online Consult

Overview

XNano The Protos pilot/commercial nanomedicine continuous manufacturing system (GMP) is a new generation nanomedicine continuous manufacturing system based on a four channel intelligent chip. It supports a single preparation volume of 500mL to 400L, integrates online dilution, flow rate monitoring, and online sampling functions, and has highly automated, closed, and disposable characteristics. It is suitable for process development and GMP production in mRNA vaccines, biopharmaceuticals, gene therapy, and other fields, and helps with innovative drug research and commercialization.

Product Details

Pilot/Commercial Nanodrug Continuous Manufacturing System (GMP)

A new generation of nucleic acid nanomedicine continuous manufacturing system based on a four channel microfluidic intelligent chip, with a single preparation range covering 500mL to 400L, integrating functions such as online dilution, two-step dilution, online flow rate monitoring, and online sampling. Breaking through the limitations of traditional equipment, empowering customers to freely develop innovative lipid nanoparticle synthesis processes (such as one-step preparation of antibody conjugated LNP and Core shell structured LNP, online dilution preparation of LNP, etc.).

Performance of XNano Protos

Preparation volume from0.5L to 400L
Chip type:Two channel/three channel/four channel, reusable/disposable
Mixed structure:Microfluidics or T-Mix, while supporting customization
Dilution type:Primary dilution/secondary dilution
throughInterTekcertification
Equipped with multi-level user permission management, audit tracking, data backup and restore functions

Characteristics of XNano Protos

Only by using "chip" intelligent manufacturing can it be true

XNano Protos' dual algorithms of イtrol and ISensor perform microfluidic mixing control in milliseconds, accurately controlling the mixing of mRNA/LNP and displaying the true flow rate in real time.

Implement consistent key quality attributes（CQA）

The Meina platform adopts the same microfluidic hybrid structure to ensure consistent key quality properties of lipid nanoparticles throughout the development process and accelerate the technology transfer from mRNA/LNP process development to GMP production stage.

Infinite innovation, 'art' in the future

The four channel chip design of Meina not only makes multiple dilution processes a reality and meets the needs of differentiated delivery systems, but also unlocks more application directions, such as one-step preparation of antibody conjugated LNP and Core shell structured LNP, online dilution preparation of LNP, etc.

Multivariate mixing method

As a platform based microfluidic device, XNano Protos not only supports microfluidic/T-Mix chips, but can also customize chips according to customer needs and provide a variety of chip materials for selection.

<<< END >>>