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New Arrivals|Mouse primary cells
1、 Overview of Mouse Primary Cells
Mouse primary cells refer to the initial cells obtained from mouse body tissues through protease or other methods and cultured in vitro to simulate the body culture (cultured cells)1Generation of cells and passage to the next stage10Cells within the generation. Its genetic material remains unchanged and can well reflect the original characteristics of cells in mice. It is widely used in molecular and cellular biology research, as well as the biopharmaceutical industry, such as drug screening and toxicology research.
2、 Classification and Specific Cells of Mouse Primary Cells
According to the source and biological characteristics of mouse primary cells, they can be classified into the following categories, with specific cells as follows:
(1) Epithelial cells
Covering the surface and lumen of the mouse body, it has functions such as secretion and absorption, and can be isolated and cultured from corresponding epithelial tissues for studying the physiological and pathological processes of mouse epithelial cells.
• Mouse Renal Tubular Epithelial Cells
• Mouse glomerular endothelial cells
• Mouse primary pancreatic acinar epithelial cells
• Mouse primary pancreatic ductal epithelial cells
• Mouse primary lacrimal duct epithelial cells
• Mouse primary middle ear epithelial cells
• Mouse primary tympanic membrane epithelial cells
• Mouse primary nasal mucosal epithelial cells
• Mouse primary cervical epithelial cells
• Mouse primary tracheal epithelial cells
• Mouse primary generationIIType alveolar epithelial cells
• Mouse primary generationⅡType alveolar epithelial cells
• Mouse primary epididymal epithelial cells
• Mouse primary small intestinal crypt epithelial cells
• Mouse primary small intestinal mucosal epithelial cells
• Mouse primary gastric mucosal epithelial cells
• Mouse primary esophageal epithelial cells
• Mouse primary scleral epithelial cells
• Mouse primary corneal endothelial cells
• Mouse primary tympanic membrane epithelial stem cells
• Mouse primary tongue epidermal cells
• Mouse primary oral mucosal epithelial cells
• Mouse primary retinal pigment epithelial cells
• Mouse primary corneal epithelial cells
• Mouse primary colonic mucosal epithelial cells
• Mouse primary placental trophoblast cells
• Mouse primary bronchial epithelial cells
• Mouse primary submandibular gland epithelial cells
• Mouse primary thyroid epithelial cells
• Mouse primary prostatic epithelial cells
• Mouse primary bladder epithelial cells
• Mouse primary ureteral epithelial cells
• Mouse primary mammary epithelial cells
• Mouse primary ovarian surface epithelial cells
• Mouse primary endometrial epithelial cells
• Mouse primary fallopian tube epithelial cells
• Mouse primary extrahepatic bile duct epithelial cells
• Mouse primary intrahepatic bile duct epithelial cells
• Mouse primary gallbladder epithelial cells
• Mouse primary conjunctival epithelial cells
• Mouse primary lens epithelial cells
• Mouse primary thymic epithelial cells
(2) Endothelial cells
Mainly located in the intima of mouse blood vessels and lymphatic vessels, distributed along the entire circulatory system, it can be isolated and cultured from tissues such as blood vessels for studying the physiological functions and related pathological mechanisms of mouse endothelial cells.
• Mouse primary femoral head microvascular endothelial cells
• Mouse primary corpus cavernosum endothelial cells
• Mouse primary mesenteric artery endothelial cells
• Mouse primary peritoneal endothelial cells
• Mouse primary pulmonary vein endothelial cells
• Mouse primary umbilical vein endothelial cells
• Mouse primary jugular vein endothelial cells
• Mouse primary cardiac microvascular endothelial cells
• Mouse primary aortic arch endothelial cells
• Mouse primary femoral artery endothelial cells
• Mouse primary abdominal aortic endothelial cells
• Mouse primary carotid endothelial cells
• Mouse primary intestinal microvascular endothelial cells
• Mouse primary pulmonary microvascular endothelial cells
• Mouse primary pulmonary artery endothelial cells
• Mouse primary coronary artery endothelial cells
• Mouse primary lymphatic endothelial cells
• Mouse primary retinal microvascular endothelial cells
• Mouse primary choroidal microvascular endothelial cells
• Mouse primary cerebral artery endothelial cells
• Mouse primary brain microvascular endothelial cells
• Mouse primary adipose derived microvascular endothelial cells
(3) Macrophages
Large white blood cells in mice have phagocytic ability and can engulf pathogens, cell debris, and other harmful substances, playing an important role in immune defense and tissue repair.
• Mouse peritoneal macrophages
• Mouse bone marrow macrophages
• Mouse primary pulmonary macrophages
• Mouse primary liverkupffercell
(4) Stellate cells
It mainly exists in tissues such as mouse liver and pancreas, and can be used as a cell screening model for new drugs for related diseases (such as chronic pancreatitis). When tissues are damaged, they will be activated and participate in tissue repair.
• Mouse hepatic stellate cells
• Mouse primary pancreatic stellate cells
• Mouse primary retinal microglia
(5) Lymphocytes
The important cell types of the mouse immune system, involved in immune recognition, memory, and immune effects, can be obtained from lymphoid tissue or peripheral blood and used to study the function of mouse immune cells and immune response mechanisms.
• Mouse primary splenic lymphocytes
• Mouse primary generationNKcell
• Mouse primary generationTlymphocyte
• Mouse primary generationBlymphocyte
• Mouse primary thymocytes
(6) Neuronal cells
The main functional unit of the mouse nervous system, responsible for transmitting and processing neural signals, can be isolated and cultured from neural tissue for studying neural development, neural signal transduction, and neurodegenerative diseases.
• Mouse primary olfactory bulb neurons
• Mouse primary trigeminal neuron cells
• Mouse primary dorsal root ganglion cells
• Mouse primary generationDRGNeuronal cells
• Mouse primary hypothalamic neurons
• Mouse primary spinal cord neuron cells
• Mouse primary hippocampal neurons
• Mouse primary cortical neurons
• Mouse primary colon neuronal cells
(7) Bone cells
Participate in the formation and repair of mouse bones, including osteoblasts, osteoclasts, etc., responsible for synthesizing and secreting bone matrix, maintaining the structure and function of bones.
• Mouse osteoblasts
• Mouse primary bone stem cells
• Mouse primary osteoclasts
• Mouse primary osteoblasts
• Mouse primary bone cells
(8) Chondrocytes
The basic cells that make up mouse cartilage tissue are responsible for synthesizing and secreting cartilage matrix, maintaining the elasticity and toughness of cartilage, and some cells participate in maintaining the stability of intervertebral discs.
• Mouse primary vertebral endplate chondrocytes
• Mouse primary chondrocytes
• Mouse primary nucleus pulposus cells
• Mouse primary fibroblast cells
(9) Mesenchymal stem cells
It has multi-directional differentiation potential and can differentiate into osteoblasts, chondrocytes, adipocytes, etc. It has broad application prospects in mouse tissue engineering and regenerative medicine research.
• Mouse primary jawbone marrow mesenchymal stem cells
• Mouse primary synovial mesenchymal stem cells
• Mouse primary adipose derived stem cells
• Mouse primary bone marrow mesenchymal stem cells
• Mouse primary placental mesenchymal stem cells
• Mouse primary umbilical cord mesenchymal stem cells
• Mouse primary epididymal adipose derived stem cells
(10) Neural stem cells
Mother cells with the potential for division and self-renewal can generate various types of cells in mouse neural tissue through unequal division, which can be used for neural development and repair research.
• Mouse primary olfactory bulb neural stem cells
• Mouse primary hippocampal neural stem cells
• Mouse primary retinal precursor cells
• Mouse primary neural stem cells
(11) Glial cells
Widely present in the central nervous system of mice, it plays a role in supporting, nourishing, protecting, and regulating neurons, and is an important component of neural tissue.
• Mouse primary spinal cord astrocytes
• Mouse primary trigeminal astrocytes
• Mouse primary enteric glial cells
• Mouse primary retinamullercell
• Mouse primary glial cells
• Mouse primary oligodendrocytes
• Mouse primary microglia
• Mouse primary astrocytes
• Mouse primary Schwann cells
(12) Adipose cells
It mainly exists in the adipose tissue of mice, participates in energy storage and metabolic regulation, and is divided into types such as brown adipocytes and white adipocytes.
• Mouse primary brown adipocytes
• Mouse primary adipocytes
• Mouse primary preadipocytes
(13) Fibroblast cells
Widely present in various tissues of mice, it has the function of synthesizing collagen and elastic fibers, playing an important role in maintaining tissue structure and repairing damaged tissues.
• Mouse primary pancreatic fibroblasts
• Mouse primary vocal cord fibroblasts
• Mouse primary extraocular muscle fibroblasts
• Mouse primary tracheal fibroblasts
• Mouse primary renal fibroblasts
• Mouse primary gingival fibroblasts
• Mouse primary ureteral fibroblasts
• Mouse primary spinal cord fibroblasts
• Mouse primary scleral fibroblasts
• Mouse primary small intestine fibroblasts
• Mouse primary gastric fibroblasts
• Mouse primary esophageal fibroblasts
• Mouse primary carotid artery fibroblasts
• Mouse primary pulmonary artery outer membrane fibroblasts
• Mouse primary abdominal aortic adventitia fibroblasts
• Mouse primary dermal fibroblasts
• Mouse primary lymphatic fibroblast cells
• Mouse primary thymic fibroblasts
• Mouse primary thyroid fibroblasts
• Mouse primary prostate fibroblasts
• Mouse primary bladder stromal fibroblasts
• Mouse primary uterine fibroblasts
• Mouse primary mammary fibroblasts
• Mouse primary liver fibroblasts
• Mouse primary colon fibroblasts
• Mouse primary aortic outer membrane fibroblasts
• Mouse primary pulmonary fibroblasts
• Mouse primary skeletal muscle fibroblasts
• Mouse primary synovial fibroblasts
• Mouse primary choroidal fibroblasts
• Mouse primary conjunctival fibroblasts
• Mouse primary cerebral vascular fibroblasts
• Mouse primary skin fibroblasts
• Mouse primary ligament fibroblasts
(14) Muscle cells
It has the functions of maintaining the stability of muscle cells, contracting muscles, etc. According to its morphological structure, function, and distribution, it is divided into three types of cells: striated muscle, smooth muscle, and myocardium.
• Mouse skeletal muscle cells
• Mouse primary atrial cardiomyocytes
• Mouse primary diaphragm cells
• Mouse primary ciliary muscle cells
• Mouse primary small intestinal smooth muscle cells
• Mouse primary gastric smooth muscle cells
• Mouse primary esophageal smooth muscle cells
• Mouse primary aortic arch smooth muscle cells
• Mouse primary arterial smooth muscle cells
• Mouse primary abdominal aortic smooth muscle cells
• Mouse primary carotid artery smooth muscle cells
• Mouse primary coronary artery smooth muscle cells
• Mouse primary bronchial smooth muscle cells
• Mouse primary tracheal smooth muscle cells
• Mouse primary pulmonary artery smooth muscle cells
• Mouse primary cerebral artery smooth muscle cells
• Mouse primary sponge smooth muscle cells
• Mouse primary fallopian tube smooth muscle cells
• Mouse primary bladder smooth muscle cells
• Mouse primary ureteral smooth muscle cells
• Mouse primary colon smooth muscle cells
• Mouse primary aortic smooth muscle cells
• Mouse primary cardiac fibroblasts
• Mouse primary cardiomyocytes
(15) Other cells
In addition to the above categories, there are various primary cells with unique biological characteristics and application value in mice.
• Mouse primary follicular membrane cells
• Mouse primary trabecular meshwork cells
• Mouse primary renal pelvis ureteral junctioncajalinterstitial cell