Multi functional lipid nanomedicine LNP preparation system

NegotiableUpdate on 05/06

Model

Nature of the Manufacturer: Producers

Product Category

Place of Origin

Online Consult

Overview

XNano The Prime type multifunctional lipid nanoparticle drug preparation system is a new generation microfluidic device that integrates advanced automation and process development functions, designed specifically for the research and screening of lipid nanoparticles (LNP). This device is a new generation of LNP microfluidic encapsulation equipment based on a four channel intelligent chip, integrating functions such as online dilution, automatic screening, process parameter optimization, and precise temperature control, breaking through the limitations of traditional equipment and empowering customers to freely develop innovative processes.

Product Details

Multi functional nano drug screening and preparation

XNano Prime is a new generation of microfluidic encapsulation equipment for lipid nanoparticles based on a four channel intelligent chip. It covers a single preparation range of 0.4mL to 120mL and integrates functions such as online dilution, automatic screening, process parameter optimization, and precise temperature control.

XNano Prime breaks through the limitations of traditional devices and empowers customers to freely develop innovative lipid nanoparticle synthesis processes (such as one-step preparation of antibody conjugated LNP and Core shell structured LNP, online dilution preparation of LNP, etc.), and expands multiple application scenarios such as gene therapy and delivery systems through customized chips.

This type of equipment is suitable for the preclinical research stage.

Performance of XNano Prime

Three functions integrated: automatic screening, prescription screening, and amplification process screening
Uniform particle size, high encapsulation efficiency, and high repeatability
Single preparation volume:0.4-120ml*
Flow rate range:1-2400ml/min*
Heating range: room temperature -80 ° C
Automatically filter and collect up to8 sets of formulas
Four channel design, dedicated to Ab LNP (tLNP, in vivo Car-T), core shell delivery, multi-step assembly/dilution and other new popular applications
Diversified mixed structure options:

Microfluidic mixing, T-mixer, as well as various customized or third-party hybrid chips
Multi level user permission management, audit tracking, compliant with FDA 21CFR part 11
Seamless amplification, consistent results

*Depending on the specific configuration

Features of XNano Prime

Infinite innovation, 'art' in the future

The design of the four channel microfluidic chip by Meina has unlocked more possibilities for the research of LNP preparation processes, such as one-step preparation of antibody coupled LNP and Core shell structured LNP, online dilution preparation of LNP, etc.

Flexible and versatile, free selection

Multi specification modular collection and adaptation system, precise matching0.4-120mLThe preparation volume range supports the synthesis of lipid nanoparticles with 8 different process parameters in a single continuous operation, significantly improving the efficiency of early research and process development.

Doubling production capacity, leading performance

The new generation of lipid nanoparticle microfluidic control preparation system integrates three core functions: online dilution, offline dilution automation, and intelligent screening. While achieving dual breakthroughs in production capacity and flexibility, we continue to maintain the industry-leading level of LNP particle size uniformity and encapsulation efficiency.

Process transfer, one step ahead

This device is innovatively equipped with a four channel intelligent integrated system, which simulates the LNP synthesis and mass production environment online, accurately predicts the fluid behavior in microfluidic devices, and achieves a rapid transition from research and development to production. The process transfer cycle is compressed by 50%, overcoming the industry problem of amplification failure!

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