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ezhou@hamilton.ch
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Room 101, Building E, Shengyin Building, No. 666 Shengxia Road, Pudong New Area, Shanghai
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Hamilton (Shanghai) Experimental Equipment Co., Ltd
Live cell concentration/cell density sensor
NegotiableUpdate on 01/18
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Overview
Live cell concentration/cell density sensor: It can measure the live cell density in solution in real-time online, and this measurement is not affected by changes in culture medium, microcarriers, dead cells, or cell debris.
Product Details
Introduction:
Incyte sensorIt can measure the density of live cells in a solution in real-time online, which is not affected by changes in the culture medium, microcarriers, dead cells, or cell debris. This measurement is widely used in biological processes such as mammalian cell culture, yeast, and high-density bacterial fermentation. Online monitoring of live cells enables real-time response to critical nodes during the monitoring process without the need for sampling.
Product advantages
Improve productivity and reduce costs
Frequency scanning function for online monitoring of changes in cellular physiological morphology
Accurately control the endpoint of continuous cultivation
Early detection of process deviations
working principle
Incyte is based on the principle of capacitance measurement, where living cells are viewed as tiny capacitors in a high-frequency electric field. The charge of these tiny capacitors is measured by sensors and presented in the form of dielectric constant (capacitance value per unit area).
| model | Conductivity range | Application Examples |
| Incyte Standard | 2-50 |
Ordinary application (such as mammalian cell culture) |
| Incyte LC | 0.5-10 | Yeast proliferation |
| Incyte HC | 5-100 |
Fermentation of acid producing bacteria (Significant pH adjustment) |
LC=Low conductivityHC=High conductivity
Living cell density and cell concentration sensorTechnical Specifications
| DN25 | A - Length | 70 mm (SG), 46 mm (DG) or 54 mm (DG-BE) |
| O-ring position | 28 mm (SG), 28 mm and 52 mm (DG) or 28 mm and 44 mm (DG BE) | |
| Process connection | G 1 1/4 ” (Ingold, Sartorius or Bioengineering) |
| DN12 | A - Length | 120， 220， 320, 420 mm |
| diameter | 12 mm | |
| Process connection | PG13.5 |
| Operating temperature range | 0 - 60℃ |
| steam sterilization | can |
| high-temperature sterilization | can |
| CIP | can |
| measurement range |
0 – 700 pF/cm, equivalent to viable cell density of: Mammalian cells in suspension 5·10^5 cells/ml to 8·10^9 cells/ml Fermenation 5 to 200 g/l dry weight |
| Conductivity range | 2 - 50 mS/cm |
Living cell density and cell concentration sensor
INCYTE - Live Cell Density Monitoring
An Incyte sensor and a preamplifier form a measurement unit, and the preamplifier can convert analog signals into digital signals.
Arc View controllers equipped with Incyte or Incyte Scan software authorization will read digital signals.
Company Introduction
HAMILTON, a Swiss company, is one of the professional manufacturers of water quality testing instruments in the world. Its process analysis products include online measurement of pH, dissolved oxygen, conductivity, redox potential, solid-state optical carbon dioxide, cell density, and total cell count. Widely used in the pharmaceutical industry, fermentation process, biotechnology, food, beer and beverage industry, sugar industry, chemical and petrochemical industry, and water treatment industry.
The HAMILTON series sensor products from Switzerland have been continuously improved in the process of innovation, gradually becoming a reliable product and ideal choice in various application fields due to their features such as * functionality, excellent quality, long service life, maintenance free, and competitive price.
HAMILTON's innovative ARC smart sensor technology no longer requires external transmitters and transfers some functions to smartphones or tablets.
