Kilby Gravity Microgravity Cultivation System

NegotiableUpdate on 05/06

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Overview

The Kilby Gravity microgravity cultivation system creates a low hydrostatic pressure and low mechanical stress microenvironment on the ground through a precision rotating device, allowing cells/animals/plants/microorganisms to grow and differentiate in a three-dimensional state closer to the body, providing a powerful tool for disease research, drug screening, and regenerative medicine

Product Details

(1)Kilby Gravity Microgravity Cultivation SystemThe core principles of technology

Beijing Kilby Biotechnology Co., LtdDeveloped and produced【Kilby Gravity Microgravity Cultivation System】By simulating the microgravity environment of space in ground laboratories, cells can be promoted to grow in three-dimensional space, thus more realistically simulating physiological conditions inside the body. ‌

This technology mainly relies onrotational motion(such as Kilby Gravity gyrator or rotating wall container bioreactor) to achieve. The cells are placed in a culture container filled with culture medium and rotated horizontally at a specific speed. This rotation keeps the cells in an environment of dynamic changes in the direction of gravity, and due to the inability of the cells to respond to rapidly changing gravity signals, it produces biological effects similar to microgravity (typically simulated at the level of 10 ⁻ g).

（2） Performance advantages of Kilby Gravity microgravity cultivation system instruments and equipment:

‌Low shear environmentThe fluid shear force generated by rotation is extremely low, which can effectively protect the integrity of fragile cells (such as neural stem cells and liver cells) and avoid mechanical damage caused by bubbles or turbulence in traditional culture. ‌

‌Promote three-dimensional aggregationUnder microgravity, cells are more likely to spontaneously aggregate and form uniform three-dimensional spherical aggregates or organoids, which are closer to the natural structure of tissues in the body. ‌

‌Optimize material transportCombined with active gas exchange and fluid flow brought about by rotation, it can efficiently transport nutrients and remove metabolic waste, avoiding necrosis inside cell clusters due to insufficient nutrition or waste accumulation, and supporting long-term cultivation.

Customizable:Micro supergravity simulation for animal, plant, and microbial ground adaptation.

Compatible with CO2 incubators/biochemical incubators,Suitable for culture bottles, dishes, centrifuge tubes, organ chips, etc

Beijing Kilby Biotechnology Co., LtdDeveloped and produced【Kilby Gravity Microgravity Cultivation System】By using precision rotating devices, a low fluid static pressure and low mechanical stress microenvironment is created on the ground, allowing cells/animals/plants/microorganisms to grow and differentiate in a three-dimensional state closer to the body, providing * tools for disease research, drug screening, and regenerative medicine.

（3） Key technical parameters:

Simulated gravity environment range	Rotating provides microgravity environment simulation (10)^-3G）， Simultaneously providing simulations of hypergravity environments (2G, 2.5G, or 3G) and lunar gravity0.17G、火星重力0.38G
Gravity monitoring capability in simulated environment	We can provide gravity monitoring in simulated environments, including X-axis, Y-axis, and Z-axis three-dimensional space gravity monitoringAnd display real-time gravity values,Accuracy ± 0.001GEnable researchers to collect real-time data on simulated environmental gravityAccurate changes.
Simulation of rotation mode and speed in microgravity environment	Simulating microgravity environment4 rotation modesThe speeds are A: 4rpm, B: 3rpm, C: 2rpm, D: 1rpm.
Simulation of rotation mode and velocity in hypergravity environment	Simulating a hypergravity environment3 rotation modesThey are 2.0G, 2.5G, and 3G respectively.
Cell culture device mounting rack type	At least 12 T25 breathable culture bottles,At least 8 specialized cell culture plates for astronaut space stations shall be used,Other specifications of cultivation devices such as culture dishes, organ chips, sphere bioreactors, etc. can be customized with mounting racks according to requirements.
Instrument operation and usage methods	Equipped with a camera to monitor the operating status of the device, it has the function of quick start (manual control) or program reservation. The instrument is operated through a touch screen, which is simple and convenient; This instrumentCan be directly placed in the incubatorFacilitating the cultivation of cells.

（4） Introduction to Some User Cases

Procurement by Shanghai Jiao Tong University Academy of Sciences, Sun Yat sen University Medical Research Center, Institute of Zoology, Chinese Academy of Sciences, Harbin Institute of Technology Space Medicine Center, Zhejiang University School of Basic Medicine and other usersBeijing Kilby Biotechnology Co., LtdDeveloped and produced【Kilby Gravity Microgravity Cultivation System】