J2 Anti dsRNA Monoclonal Antibody Proxy

J2 monoclonal antibody (mAb), mouse, IgG2a, kappa chain

J2monoclonal antibody(mAb), mice,IgG2a，kappachain

J2Monoclonal antibody（mAb J2）It is of mouse originIgG2aType antibody, targeting bothRNA（dsRNA）Its recognition ability makes it play an important role in virus detection and research.J2Antibodies were initially developed for the detection of plant viruses, but as research progressed, their application scope rapidly expanded.2006In the year,WeberIn a study, it was confirmed that,J2Antibodies can detect all positive chains within infected cellsRNAThe large amount produced by the virusdsRNAThis discovery makesJ2Antibody becomes a testdsRNAThe 'gold standard' has been established and promoted its widespread application in related fields, with over200Publish relevant literature.

J2monoclonal antibodyFeatures and Applications

J2Antibodies can recognize lengths greater than or equal to40 bpofdsRNAThe recognition process does not rely on the sequence or nucleotide composition of the antigen. After research, it was found thatJ2Antibodies can recognize various naturally occurring substancesdsRNAThis includes hepatitis C virus, dengue virus, rhinovirus, chikungunya virus, rabies virus, poliovirus, swine fever virus, and wheatgrass mosaic virus. This makesJ2Antibodies have become a tool in virology research. This antibody is suitable for various experimental techniques, including enzyme-linked immunosorbent assay（ELISA）ThedsRNAImmunoblotting, immunoaffinity chromatography, and immunohistochemistry in certain systems. It should be noted that during the processdsRNABefore immunoblotting, nucleic acid must be separated by polyacrylamide gel electrophoresis, because the sensitivity after transfer from agarose gel will be significantly reduced. In addition,J2Antibodies are not suitable for clinical use and are limited to in vitro experiments.

J2monoclonal antibodyStorage and stability

Before use,J2Monoclonal antibodies are typically provided in freeze-dried form. After reconstitution, it is recommended to pack and store it separately-20°Cor-70°CTo ensure its activity and stability.

J2monoclonal antibodyResearch background and literature support

J2The development of monoclonal antibodies is based on double stranded antibodiesRNAA deep understanding of the structure. as early as1991In the year,SchönbornResearchers have already published relevant studies demonstrating the effectiveness of dual chain technologyRNAHow to use monoclonal antibodies as nucleic acid extractsRNAStructural probe. In the following years,LukacsThe researchers further explored the application of this antibody in the detection of plant virus infections and proposed a method for distinguishing coexisting viruses using monoclonal antibodies. These studies areJ2The widespread application of antibodies has laid the foundation. At present,SCICONSThe company is a provider of dual chain servicesRNAManufacturer of molecular hybrid mouse monoclonal antibodies, whose products includeK1TheK2andJ2Monoclonal antibodies.SCICONSHeadquartered in Hungary, with customers worldwide35A country, including the United States50More than half of the states use itSCICONSMonoclonal antibodies. The company is committed to providing high-quality research tools for international research institutions and has gained recognition from numerous scholars.

J2Monoclonal antibody ordering

References
Schönborn, J., Oberstrass, J., Breyel, E., Tittgen, J., Schumacher, J. and Lukacs, N. (1991) Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extracts. Nucleic Acids Res.19, 2993-3000.

Lukacs, N. (1994) Detection of virus infection in plants and differentiation between coexisting viruses by monoclonal antibodies to double-stranded RNA. J. Virol. Methods 47, 255-272.

Lukacs, N. (1997) Detection of sense:antisense duplexes by structure-specific anti-RNA antibodies. In: Antisense Technology. A Practical Approach, C. Lichtenstein amd W. Nellen (eds), pp. 281-295. IRL Press, Oxford.

SCICONSCompany Profile

HungarySCICONSIt is a global company that can provide dual chain servicesRNAMolecular hybridization of mouse monoclonal antibodies, withK1Monoclonal antibodiesK2Monoclonal antibodies andJ2Monoclonal antibodies.
English & Scientific Consulting Kft.namelySCICONS, headquartered in Szilaku, Hungary(sirens).SCICONSOur customers are spread all over the world35A country, while the United States50More than half of the states are using itSCICONSMonoclonal antibodies.SCICONSThe customer base includes many scholars from international research institutions who have published200Multiple articles, visible links:documented by over 200 scientific articles.

NORDIC MUBIOCompany Profile

Nordic-MUbioDevelop and manufacture high-quality antibody reagents for research and development. All products are strictly in accordance withISO 9001Our focus is on developing antibodies against cell adhesion proteins, nuclear proteins, and cytoskeletal proteins in the manufacturing of quality guidelines.

Nordic-MUbioWe are currently one of the antibody companies that research and develop antibodies for zebrafish50 Multiple antibodies have been validated for immunofluorescence in zebrafish.

In collaborative development projects,Nordic-MUbioWe are researching, testing, and validating antibodies and antigens for diagnostic applications in the field of lung cancer and other cancers.