Irrigation swinging precision shaker for organoids

NegotiableUpdate on 05/06

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Overview

In traditional static cultivation, the core of organoids is often prone to necrosis due to insufficient nutrition and oxygen. Beijing Kilby Biotechnology Company's perfusion swinging precision shaker for organoids solves this bottleneck problem through continuous perfusion, enabling organoids to grow and differentiate healthily for a long time

Product Details

3D technology developed and produced by Beijing Kilby BiotechnologyIrrigation swinging precision shaker for organoids

①In traditional static cultivation, the organoid coreoftenIt is prone to necrosis due to insufficient nutrition and oxygen. Beijing Kilby Biotechnology Co., Ltd3DIrrigation swinging precision shaker for organoidsBy continuously perfusing, this bottleneck problem has been solved, enabling organoids to grow and differentiate healthily in the long term.

②Provide a fluid dynamic environment with low shear force, avoiding violent stirring or rotation that can harm fragile structures3D organoid structures cause damage.By precisely controlling the angle and frequency of oscillation, controllable fluid flow is generated to ensure that nutrients and oxygen are evenly delivered to each organoid, while timely removing metabolic waste.Using this system can cultivate moreLarge sized, more mature, and closer to the physiological state of the body's organoids.

③This instrument canCompared to standard porous plates (such as6-hole, 12 hole, 24 hole plateswait）Compatible,It can also be adapted to organoid chips,orGlass bottomed culture dishwait，Allow for a large number of parallel experiments to be conducted simultaneously, meeting the needs of high-throughput applications such as drug screening.

Attachment:Comparison with traditional shaker and static cultivation

characteristic	Beijing Kilby Biotechnology Co., Ltd3DSwing type precision shaker for organoids	traditionOrbital shaker	Static cultivation (porous plate)
shear force	extremely lowGentle swaying	higherRotation may damage organoids	nothingButdiffusion 受限
nutrition/Gas exchange	excellentContinuous infusion, active exchange	betterEnhance through liquid level movement	poorRelying solely on diffusion, the core is prone to necrosis
Cultivate consistency	tallEach sample has uniform conditions	generalThere may be differences between the center and the edge	generalThere may be differences between the holes
degree of automation	tall，CanOptional irrigation moduleLong term unmanned operation	low, manual fluid change is required	lowFrequent manual fluid change is required
Application scenarios	advanced3D modelLong term experiments, high-throughput screening	Suspended cells, bacterial culture, simple3D sphere	2D cells, early organoid formation