InertCore Plus C18 chromatographic column 150x4.6mm 2.6um

GL Sciences Core Shell ColumnIt has the characteristics of low back pressure and high column efficiency, and is widely used in LC-MS/MS and high-throughput analysis. Compared to ordinary fully porous silica gel liquid-phase columns, the core-shell silica gel structure has a porous surface with a solid core inside, making it characterized by fast peak extraction and high column efficiency. A particle size of 2.6 μ m can match the column efficiency and separation efficiency of a fully porous silica gel column with a sub 2 μ m. GL Sciences has devoted itself to research and development, launching the InertCore series of core-shell columns, which will assist your analysis with its high batch reproducibility.

InertCore Plus C18 chromatographic column 150x4.6mm 2.6umProduct Parameters:

Matrix: Core shell silicone

Particle size: 2.6 µ m

Core diameter: 2.0 µ m

Surface area: 200m ²/g

Micropore diameter: 90 Å (9 nm)

Chemical bonding group: octadecyl

End and end sealing treatment: Yes

Carbon content: 15%

USP Code: L1

Recommended pH range: 1-10

Pressure tolerance: 100 MPa (inner diameter 2.1 mm) 60 MPa (inner diameter 3.0 mm, inner diameter 4.6 mm)

*: Converted separately to remove the surface porous silica layer of the core

InertCore Plus C18 chromatographic column 150x4.6mm 2.6um,Both HPLC and UHPLC can be used

Two liquid phase analysis systems, InertCore Plus C18, were used for testing under the same analysis conditions. Both systems exhibited good peak shapes and obtained similar spectral results. (In the experiment, only certain adjustments were made to the gradient elution program, while other analytical conditions remained consistent, in accordance with the provisions of the European Pharmacopoeia for changes in analytical methods.)

Under the condition of using UHPLC

Under the conditions of using HPLC

Ordering information:

InertCore Plus C18 Analytical Column

The accessory connection type used is Parker type (UP type).

InertCore Plus C18 protective column

The accessory connection type used is Parker type (UP type).

InertCore series core-shell columnProduct Features

▪ Surface porous structure, faster peak emergence

▪ High theoretical tray number, enhanced peak shape of acidic and alkaline compounds

▪ Low back pressure, wide pH tolerance range

▪ Similar to the efficiency of sub 2 μ m packing column

Core shell silica gel technology with high theoretical tray number

When using a core-shell column for analysis, the molecules of the tested compound only need to pass through the porous surface of the core-shell silica gel in the chromatographic column. Core shell silicone is different from ordinary fully porous silicone, as it has a solid core structure inside and relatively low diffusion inside the micropores. Therefore, when using a core-shell column, the elution band of the test compound from the chromatographic column is narrower and the theoretical plate number is higher.