Human umbilical artery smooth muscle cell line

Introduction to immortalized human umbilical artery smooth muscle cells:

Although primary human umbilical artery smooth muscle cells can more accurately reflect the physiological state of umbilical artery smooth muscle cells in the human body, on the one hand, the long cell cycle of primary isolated and cultured human umbilical artery smooth muscle cells and the high requirements for technical personnel's experience, and on the other hand, these primary cells cannot be passaged multiple times in vitro, which restrict the widespread application of primary human umbilical artery smooth muscle cells in the laboratory. The research team of Xinrun Biology has years of experience in primary cell isolation, culture, and cell immortalization services, and has successfully established immortalized human umbilical artery smooth muscle cells.

The umbilical cord is the connecting structure between the fetus and the placenta. Shaped like a rope, with a smooth and transparent surface, containing connective tissue and a pair of umbilical veins and arteries. Recent studies have shown that smooth muscle cells can express calcium ion channels, ICAM-1, and VCAM-1. The expression of ICAM-1 and VCAM-1 may be the cause of vascular wall inflammation and further contribute to vascular diseases. Therefore, in vitro culture and research of vascular smooth muscle cells can be used to discover and determine targeted therapies for new vascular diseases.

Our company produces immortalized human umbilical artery smooth muscle cells using enzymatic hydrolysis and gene transfectionPrepared, with a total cell count of approximately 1 × 10⁶/The T25 square bottle has a cell purity of over 90% and does not contain HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, fungi, etc.

Culture medium information:

We recommend using the product developed by Xinrun BiotechnologyImmortalized human umbilical artery smooth muscle cell culture medium(Product Code: IH1008-5) is used as a culture medium for in vitro cultivation of immortalized human umbilical artery smooth muscle cells.