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Human peripheral blood B lymphocyte lineage

NegotiableUpdate on 05/06
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Overview

The progenitor cells of B lymphocytes exist in the island of hematopoietic cells in fetal liver (embryonic mice at 14 days or 8-9 weeks), and thereafter the site of B lymphocyte production and differentiation is gradually replaced by bone marrow. Mature B cells mainly settle in the superficial layer of lymph node cortex lymph nodes and in the red and white pulp lymph nodes of the spleen. B cells can differentiate into plasma cells under antigen stimulation, and plasma cells can synthesize and secrete antibodies (immunoglobulins), mainly performing humoral immunity in the body.

Product Details

Human peripheral blood B lymphocyte lineageIntroduction:

Although primary human B lymphocytes can more accurately reflect the physiological status of B lymphocytes in the human body, on the one hand, peripheral blood tissue is very precious, and the isolation and cultivation of primary human B lymphocytes have a long cycle and require high experience from technicians. On the other hand, the growth cycle of these primary cells in vitro is very short, making it difficult to isolate and cultivate primary human peripheral blood B lymphocytes each time. These unfavorable factors limit the widespread application of primary human B lymphocytes in the laboratory. The research team of Xinrun Biology has years of experience in primary cell isolation, culture, and cell immortalization services, and has successfully established immortalized human B lymphocytes.

The products produced by our companyHuman peripheral blood B lymphocyte lineagePrepared using density gradient centrifugation and gene infected human peripheral blood B lymphocytes, with a total cell count of approximately 1 × 106/The T25 square bottle has a cell purity of over 90% and does not contain HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, fungi, etc.

Culture medium information:

We recommend using the product developed by Xinrun BiotechnologyImmortalized human peripheral blood B lymphocyte culture medium(Product Code: IH1015-5) as an in vitro cultureImmortalized human peripheral blood B lymphocytesThe cultivation medium.