Dynamic colon bioreactor

Dynamic colon bioreactorProduct Introduction

Dynamic colon bioreactorNot only can it simulate the fermentation process of the large intestine during human digestion, but it can also be scaled up and used in actual fermentation production processes. The current bioreactors used for solid fermentation (agitation, drum, fluidization, semi continuous agitation) are difficult to promote particle dispersion. Stability, production efficiency, and mass and heat transfer are also difficult to solve problems. Especially difficult to avoid oxygen limitation, the new biomimetic colon bioreactor can effectively improve this problem.Dynamic colon bioreactorIt is a new type of reaction device that utilizes tank wall creep to achieve mixing, and this type of mixing system is very different from the stirring in traditional bioreactors. Under the action of external force, a concentric muscle contraction pattern similar to that occurring in the colon is formed. It has shown certain advantages in both laboratory and industrial settings.

Dynamic colon bioreactorBiomimetic peristaltic mixing regulation helps prevent excessive aggregation of reaction substrates, high pressure drop, and the occurrence of cracks and grooves in the bed layer; Avoid inhibiting growth due to low water activity in the bed as the reaction progresses;Dynamic colon bioreactorFor microbial fermentation that produces enzymes, it is easy to form lower reducing sugars and higher levels of soluble proteins and enzyme activity, especially for solid samples containing a small amount of water layer (humidity about 70%); At the same time, it can save time and costs related to cleaning and sterilization, and is suitable for some special reaction substrates (such as high viscosity and corrosive substrates of traditional stainless steel reactors).

Dynamic colon bioreactorProduct Features

Flexible fermentation tank

Efficient mixing: multiple extrusion modes

Automatic control: dissolved oxygen, pH

Accurate temperature detection and control with dual probes inside and outside

Dynamic colon bioreactorFunction and configuration

Capacity 300-800mL

Automatic intake module: 2 rotor flow meters

Exhaust module

Inlet/outlet module: peristaltic pump * 4

Mixing and Mixing Module: Squeezing Plate * 4

Interfaces and accessories: 6 liquid/gas interfaces, 2 temperature interfaces, 1 pH interface, 1 dissolved oxygen interface

Real time recording and storage of data