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Nanjing Hexi Biotechnology Co., Ltd
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Dynamic axial compression column

NegotiableUpdate on 05/18
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Overview

The dynamic axial compression column is an automatically packed chromatographic column developed for industrial high-pressure preparation of chromatography. Industrial preparation chromatography system is a customized separation and purification equipment for customers. It is based on the principle of preparative liquid chromatography and incorporates an industrial automatic control unit to achieve the entire production process of automatic column loading and collection of materials. The main products include 50mm DAC, 100mm DAC, 150mm DAC, 200mm DAC, 300mm DAC, and 600mm DAC.

Product Details

Dynamic axial compression columnIt is an automatically packed chromatography column developed for industrial high-pressure preparation chromatography.

The main products include 50mm DAC, 100mm DAC, 150mm DAC, 200mm DAC, 300mm DAC, and 600mm DAC.

Dynamic axial compression columnThe main application areas are:

(1) Purification of high value-added products such as paclitaxel.

(2) Production of products with large sample size and low added value (such as steviol glycosides and other low added value pharmaceutical excipients).

(3) Process improvement products (products that increase production or improve product purity).

Product Features:

(1) The column installation time is short, and there is no need for secondary disassembly and assembly, so it can avoid the impact of column bed rebound on column efficiency during disassembly and assembly of traditional chromatography columns.

(2) The piston head is always in contact with the column bed and maintains the column loading pressure, avoiding the problem of column bed collapse after long-term use of traditional chromatography columns and extending their service life. 3) The advantages of our company's Dynamic Axial Compression Chromatography Column (DAC) over other manufacturers' products are that it does not use electrical components and can be used in explosion-proof areas (or hydraulic stations with explosion-proof motors can be used)

1) Replace the pneumatic hydraulic amplification pump with a hydraulic station. Its advantage lies in the gentle output pressure of the hydraulic station, the constant descent of the hydraulic cylinder, and the avoidance of the impact force caused by the intermittent output of the pneumatic hydraulic amplification pump, which not only protects the packing but also avoids the overall impact of the equipment on the ground.

2) The pipeline layout is more concise. Only the two oil pipes connecting the hydraulic cylinder are highly integrated, with better overall integrity. Larger and more convenient space for disassembling and assembling chromatography columns.

3) Two power sources, pneumatic and electric, can be used. In certain specific situations, the output pressure and generated compressed air volume of compressed air cannot meet the needs of pneumatic hydraulic amplification pumps, resulting in insufficient column installation pressure and long column installation time, which affects column efficiency. At the same time, some laboratories do not have compressed air, and using gas cylinders or air compressors will incur additional costs and noise. The explosion-proof motor used for electric drive can use the same power supply as the pump and detector.

4) On DACs with a diameter exceeding 800mm, the installation time of pneumatic hydraulic amplification pumps will be significantly prolonged due to flow and pressure limitations. By using a hydraulic station, a pump with high flow rate and low pressure can be used to achieve rapid column installation, while a small pneumatic hydraulic amplification pump can be used to maintain pressure after column installation is completed.