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Dual channel non-contact ultrasonic DNA disruptor

NegotiableUpdate on 01/21
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Overview
The research fields of dual channel non-contact ultrasound DNA disruptor include modification research of n histones, epigenetic modification research of chromatin, transcriptional regulation analysis, drug development research, mitosis research, DNA damage and apoptosis analysis, etc.
Product Details

Dual channel non-contact ultrasonic DNA disruptorModel: XM-150A

The non-contact ultrasonic DNA disruptor uses isothermal and non-contact methods to break, homogenize, and mix samples. Used for sterile, ultra micro disruption of chromosomes through centrifuge tubes. Specially tailored for pre-processing of second-generation sequencing DNA samples and chromatin immunoprecipitation experimental samples.

Non contact samples can be crushed in a closed container without producing infectious flying mist. The ultrasonic probe does not come into contact with the sample to avoid cross contamination. For laboratories that handle multiple samples or valuable samples every day, non-contact ultrasonic DNA disruptors have advantages such as high-throughput processing, low sample loss, and no cross contamination. Gradually becoming a standardized tool for ChIP (chromatin immunoprecipitation) and DNA splicing research platforms.

Dual channel non-contact ultrasonic DNA disruptorBasic Principles:

By using piezoelectric converters, electrical signals are converted into high-frequency acoustic signals, generating millions of molecular "holes". The instantaneous fluid shear force generated by the enlargement and rupture of "holes" within a few seconds is utilized to break, homogenize, and mix the sample in an isothermal, non-contact manner.

Main applications:

Bacterial cell lysis, protein extraction, immunoprecipitation experiments, second-generation sequencing samples, fungal spore fragmentation/emulsification, DNA fragmentation, homogenization/accelerated dissolution/catalytic reactions, etc

Performance characteristics:

The instrument is equipped with a rotating motor, which automatically rotates the centrifuge tube adapter continuously during ultrasound, making the ultrasound energy distribution more uniform

Simple operation, fast time, usually the shortest time for an experiment is only 5 minutes

The microprocessor controller is equipped with password protection function, which allows for free editing of programs and automatic memory of set programs

Adopting a 7-inch medical grade resistive touch screen for touch operation, the screen displays real-time working parameters such as time, temperature, power, continuous mode, and gap mode. The operation is simple and convenient, with a countdown display of the running status

The instrument has overcurrent, overvoltage, and overtemperature alarm functions. When the temperature exceeds the set temperature, it automatically stops ultrasound and alarms to ensure the integrity of the sample

Comparison between traditional probes and non-contact probes:

Main functional features:

1. High throughput, capable of processing 32-64 samples simultaneously, with high experimental efficiency;

2. No need to frequently operate the probe, all samples are in separate fully enclosed test tubes to avoid cross contamination;

3. Rich product configuration with various adapters ranging from 0.1ml to 15ml, suitable for experiments on different samples;

4. Using a 4 ℃ low-temperature water bath ultrasound, the energy distribution is uniform, and the ultrasound effect is applied to the sample in a low-temperature environment, avoiding sample denaturation;

5. The ultrasound parameter settings are flexible, the experimental steps are standardized, the experimental repeatability is good, and the reliability of the results is high.

6. Simple operation and fast time, usually only a few minutes are needed for an experiment:

7. No special consumables are required, and the experimental cost is low.

Technical Specifications