DSI BUXCO non-invasive dual chamber special airway resistance detection system

Awakening Experimental Animal Detection System - NAM (Non Invasive Special Airway Resistance sRaw Detection)

The NAM (Non Invasive Airway Mechanics) non-invasive dual chamber detection system is suitable for non-invasive monitoring of lung ventilation function in conscious experimental animals. By detecting the phase difference between nasal airflow and chest airflow, the special airway resistance (sRaw) is calculated. It is currently widely accepted as an ideal indicator to replace invasive detection and has been widely recognized as a non-invasive detection standard in the industry for nearly 30 years, replacing EF50 and Penh. It is an ideal tool for longitudinal research on airway resistance in conscious animals.

Applicable species: mice, rats, guinea pigs

The cavity adopts Allay ™ The restraint device of the technology integrates pneumotach and reference chamber, which ensures that animals maintain a natural breathing state during the monitoring process, avoiding chest and abdominal compression and respiratory obstruction, greatly reducing the adaptation time of animals.


Halcyon ® The noise reduction design of the cavity detects signals from two channels leading to the animal chamber and the control chamber through two detection ports of the sensor, in order to distinguish external interference signals and signals generated by animal respiration, thereby eliminating noise, including internal vibration interference caused by animal activities and noise caused by door closing, air ventilation ducts or other air disturbances, further improving data accuracy and reliability.

NAM system features:

Sustainable detection of special airway resistance (sRaw) in conscious non-invasive experimental animals
Fully automatic calibration avoids the tedious work and uncertainty of manual daily calibration
• Standard atomization drug delivery function
The system comes standard with two types of workstations: dual chamber and four chamber. If four animals need to be tested simultaneously, the four chamber version is optional.
Easy to expand, multiple workstations can be connected via USB, and a single FinePointe system can detect up to 16 animals simultaneously.
Flexible configuration, the same workstation can accommodate chambers of different sizes, and users can freely replace them.

Advantages of NAM system:
Two way communication ensures the accuracy and reproducibility of scientific data
• One click automated quick calibration to avoid manual errors
• Nebulization dosing calibration - avoids differences in dosing efficiency among different controllers
• Automatic bias current rate - custom reduction of bias current during exposure administration process
• Bias current meter noise reduction technology - improving signal-to-noise ratio
Finepointe software - professional integration of multiple respiratory related studies and automatic report generation function

Main parameters of NAM system:

Respiratory rate, tidal volume, minute ventilation, special airway resistance, special airway conductance, airway resistance, functional residual gas volume, peak inspiratory flow rate, peak expiratory flow rate, inspiratory time, expiratory time, delay time of airflow from chest to nasal cavity, time ratio required to reach peak expiratory flow rate, expiratory flow rate at 50% ventilation volume, etc.