DMT in vitro microvascular tension measurement system

NegotiableUpdate on 05/06

Model

Nature of the Manufacturer: Producers

Product Category

Place of Origin

Online Consult

Overview

The DMT 620M/630M in vitro microvascular tension measurement system is a sophisticated and durable research equipment. Four channels can measure the tension changes during the contraction and relaxation process of isolated microvessels with a diameter of over 30 μ m, reflecting the physiological function of the isolated blood vessels. The needle fixed frame sample supports a maximum diameter of up to 7mm. It is an ideal device for scientific research projects such as cardiovascular physiological mechanisms, smooth muscle contraction function, endothelial cell relaxation function, ion channels, and drug screening.

Product Details

Newly developed by DMTDMT630MA in vitro microvascular tension measurement systemAdded microvascular initial pre tension automatic stretching program（620MFor manual micro spiral ruler stretching, used to optimize the initial pre tension values of different types of isolated microvessels. After the ex vivo microvascular samples are fixed, the built-in microvascular initial pre tension automatic stretching program in 630MA will automatically stretch the microvessels to the optimal initial pre tension (620M does not have this function), ensuring experimental stability and repeatability without manual stretching and calculation, avoiding human errors and differences between samples, and ensuring the repeatability and stability of experimental data. During the experiment, the circumference of the blood vessels remains constant, meaning that the vessels will undergo an equal length contraction process. Medications can be directly added to the bath, and their effects and physiological functions can be reflected by measuring the tension changes during microvascular contraction and relaxation.

630MA / 620MSimultaneously providing two signal output modes: analog output and digital output. It can be directly connected to a computer through a USB cable, and the DMT host driver can output data signals to the BIOPAC physiology analyzer for signal conversion without the need to connect an amplifier. In addition, multiple 630MA/620M instruments can be connected to the same computer to form an eight channel or sixteen channel system, using the same software to simultaneously collect signals, making it an ideal device for high-throughput drug screening experiments. This instrument is particularly suitable for vascular pharmacology and physiology research, and is an ideal equipment for cardiovascular research experiments.

DMT 离体微血管张力测定系统

System Features

Simultaneously measure four isolated microvascular samples

● Built in microvascular initial pre tension automatic stretching program (only 630MA)

● Built in heating and electric control valve can quickly remove waste liquid at the same time

The sample can maintain activity for more than 12 hours

Ideal equipment for high-throughput drug screening experiments and dose-response curve experiments

Clamp type fixation bracket is used to fix microvessels with diameters ranging from 30 μ m to 450 μ m; Needle fixation bracket is used to fix blood vessels with a diameter of 450 μ m or more, with a maximum of 7mm

Technical Features

● Integrated heating, medication administration, and drainage

● Intuitive data flow

● selectable force range (mN)

● Integrated calibration program

● Intuitive touchscreen interface menu

● Compact design/small footprint

● Multi functional - muscle movement recorder and organ bath combined into one

Acid resistant stainless steel chamber (to avoid adhesion of lipids/compounds)

Circular installation section>30 μ m/<10mm

● Automatic standardization (preloading tension)

● Small chamber volume