Cold and hot plate instrument

1、 Overview:
Cold and hot plate instrumentAt present, the screening experimental methods (physical methods) for acute pain analgesics are mainly hot plate experiments, tail flick reflex experiments, or animal foot tenderness irradiation experiments. However, these are all normal stimulus response thresholds for animals and belong to a type of physiological pain. There is a fundamental difference between physiological pain and pathological pain. Physiological pain is a self-protection alarm system for survival, while pathological pain is a disease that hinders survival. Due to the different manifestations and mechanisms of the two types of pain, the experimental methods for studying analgesic drugs are also different. For example, some analgesic drugs have good analgesic effects on physiological and pathological pain. But some drugs only have an effect on physiological pain, so different experimental methods and instruments can be used to screen drugs with different points of action. Cold and hot plate pain tester is an instrument that can perform physiological pain experiments and pathological pain experiments on the same instrument.
Cold and hot plate instrumentWhen the surface temperature is set to 4 ℃, the test drug can significantly change the lifting time and frequency on the cold plate for animals that cause pathological pain in the ischium. When the surface temperature is set to 55 ℃, the physiological pain threshold of the animal can be accurately measured to determine the type and effect of the test drug's analgesia. The advantage of this experimental method is that the animals are tested in an unconstrained state, avoiding human interference and harm to the animals. It is loved by experimenters for its simple and convenient operation, clear indicators, and ability to more accurately reflect the pain behavior of animals.
In addition to the basic requirements of a wide set temperature range (-5 ℃~70 ℃), high temperature control accuracy, and small timing (0.01 seconds), this instrument also has advantages such as LCD Chinese display, built-in micro printer, USB microcomputer interface, fast animal packaging, complete data display, convenient animal observation, automatic accumulation of foot lifting time and times, etc. It is a truly one machine dual-use analgesic drug experimental instrument.

2、 Technical parameters:

1Temperature setting:-5℃~70℃ Adjust the step size to0.1℃

2Temperature fluctuation: ≤±0.1℃
3Timing:0.01second
4、25℃ drops to4℃ time: ＜5minute;
5、25℃ rises to55℃ time: ＜3minute;
6Cold plate area: diameter190mm
7Observation box size: diameter190mm, height220mm
8、5Chinese display on inch LCD touch screen

9. Screen resolution: 800X600

10. 1~99 groups with grouping function

11. Record parameters: group, temperature, experimental time, pain threshold time, number of foot lifts, single foot lift time, cumulative total foot lift time
12WithUSBImport data into the mouthUplate

13Internal clock
14Touch button, foot switch trigger
15, optionalRS232External thermal printer for data printing report
16Operating environment humidity:20%RH～80%RH
17Power supply:110V~AC220V±10% 50Hz
18Input power:180W
19Overall dimensions:260*260*155mm

Nanjing Calvin Biotechnology Co., Ltd. (Calvin Biotech) is a professional provider of life science experimental equipment.
Calvin Biotech's main products include animal treadmills, sleep deprivation devices, cold and hot plate pain gauges, autonomous activity wheels, animal anesthesia machines, and brain stereotaxic/injection devices，Pain/inflammation testing system, non-invasive blood pressure measurement system; Behavioral equipment such as self-administration systems for rats and drug addiction testing systems.
Calvin Biotech adheres to customer demand orientation, continuously strengthens research and development investment and product innovation, introduces * production and testing equipment, and provides high-quality solutions for our customers. The company has always adhered to the principle of "quality first, technological innovation as the foundation", adhered to the purpose of "providing * solutions for medical and social progress", focused on people-oriented, encouraged technological innovation, and determined to develop into a reliable domestic manufacturer and service provider of biological instruments.

Calvin Biotech mainly engages in sales agency work for imported products in related fields and domestic products with high technological content. Due to the rapid updates of new technologies, concepts, and methods in this field, the work is quite challenging. We welcome ambitious individuals to join us!