Biotin-Etalocib， Biotin Etaloxib

Biotin-Etalocib， Biotin EtaloxibIt is a conjugate formed by the chemical connection of Biotin and Etalocib, which combines the labeling properties of Biotin with the pharmacological activity of Etalocib, demonstrating special application value in the fields of medicine and biotechnology.

Chemical Structure and Composition

• BiotinWater soluble vitamin B7, with a molecular structure consisting of a lipid soluble heterocyclic ring and a hydrophilic carboxylic acid chain. Its carboxyl group can react with various functional groups, while heterocycles can specifically bind to avidin or streptavidin, forming high affinity complexes.

• EtalocibA leukotriene B4 (LTB ₄) receptor antagonist. It has anti-tumor potential by inhibiting LTB receptor activity, blocking neutrophil activation, and inducing cell apoptosis.

• connection methodBiotin and etazomib are covalently linked to form a stable conjugate, retaining the core functions of both parties.

characteristic

1. Dual function collaboration：

• Biotin endProvide specific labeling ability that can bind with streptavidin to achieve targeted delivery or signal amplification.

• Etaloxib EndMaintain antagonistic activity against LTB receptor and induce tumor cell apoptosis.

2. High affinity and stability：

• The biotin streptavidin complex binds stably and irreversibly, making it suitable for long-term labeling and detection.

• Etaloxib maintains its activity under physiological conditions to ensure pharmacological effects.

3. biocompatibility：

• Biotin, as an endogenous vitamin, has low toxicity; Etaloxib is a small molecule drug with a clear metabolic pathway, and the overall safety of the conjugate is relatively high.

Precautions for use

• Storage conditionsIt is recommended to store at -20 ℃ in the dark to maintain the stability of the compound.

• solubilityEasy to dissolve in DMSO and methanol, attention should be paid to solvent selection when preparing the solution.

• Scope of applicationCurrently, it is mainly used in the field of scientific research.

Biotin-Etalocib， Biotin Etaloxib

About Us:

The product categories operated by Shaanxi Xingbei Aike Biotechnology include synthetic phospholipids, polymer polyethylene glycol derivatives, block copolymers, magnetic nanoparticles, nano gold and nano gold rods, near-infrared fluorescent dyes, reactive fluorescent dyes, fluorescent markers, protein crosslinking agents, small molecule PEG derivatives, click chemistry products, dendritic polymers, cyclodextrin derivatives, macrocyclic ligands, fluorescent quantum dots, hyaluronic acid derivatives, graphene or oxidized graphene, carbon nanotubes, fullerenes, silica and mesoporous silica, polymer microspheres, near-infrared fluorescent dyes, polystyrene microspheres, upconversion nano luminescent particles, MRI magnetic resonance imaging products, fluorescent proteins and fluorescent probes, etc.

Kind reminder: The supplied product is only for scientific research and cannot be used for human body!

Related products:

Biotin-Dodecylamine， Biotin dodecyl primary amine

Biotin-Tridecylamine， Biotinyl-n-tridecaneamine

Biotin-Tetradecylamine， Biotin Tetradecylamine

Biotin-Pentadecylamine， Biotin pentadecanamine