Bcl-2 recombinant rabbit monoclonal antibody

1、 Basic Product Information

Product English Name:Bcl-2 Recombinant Rabbit Monoclonal Antibody

Product Chinese Name:Bcl-2Recombinant rabbit monoclonal antibody

Product AliasApoptosis regulator Bcl-2Antibody;BcellCLL /lymphoma2 Antibody;PPP1R50antibody

Product Specifications20μL, 50μL, 100μL

2、 Product specific parameters

Host: Rabbit

monoclonalorPolyclonal: Monoclonal

Clone number: not provided

Subtype:IgG

Reaction species: human, mouse, rat

Application:Western Blot (WB)Immunohistochemistry (paraffin sections,IHC-P）Immunocytochemistry（IF-C）Immune tissue fluorescence（IF-T）Immunoprecipitation（IP）Flow cytometry（FCM）

Immunogen: human sourceBcl-2Recombinant protein, amino acid range:1-230

Concentration:1.165 mg/mL

Form: Liquid

Purification process: Affinity chromatography

Storage solution:PBS, including50%Glycerol0.5% BSAand0.02%Sodium azide

Transportation conditions: ice pack or dry ice transportation

Recommended short-term storage time and conditions: Upon receipt- 20°CSave, stable within one year.

Recommended long-term storage conditions:-20°COr store at a lower temperature in the dark. No need for packaging.

IIIProduct Details

This product is designed for human sourcesBcl-2Recombinant rabbit monoclonal antibody for protein, item numberAWA10156.Bcl-2Recombinant rabbit monoclonal antibody purified by affinity chromatography has high specificity and sensitivity, and can effectively detect endogenous antibodiesBcl-2The predicted and observed molecular weights of the protein are26 kDaThe product is suitable for various experimental techniques, includingWestern Blot(Recommended dilution ratio)1:1000-1:10000）Immunohistochemistry (paraffin sections,1:100-1:1000）Immunofluorescence (Cellular)/organization1:50-1:1000）Immunoprecipitation（1:100-1:300）And flow cytometry（1:50-1:200）. Experimental data shows that the antibody is effective in humans (such as...)JacketTheK562TheHelaCells), mice (such asRaw264.7It showed good performance in various samples such as cells, brain, spleen, lung tissue, and rat (brain, spleen tissue).

4Target information

Bcl-2（BCell lymphoma- 2）Yes, it isBcl-2An important member of the protein family, as a key anti apoptotic protein, plays a central role in regulating the programmed cell death (apoptosis) pathway. It mainly inhibits mitochondrial outer membrane permeability and prevents cytokine productioncEqual release of pro apoptotic factors from mitochondria to cytoplasm, thereby blockingcaspaseThe activation of cascade reactions promotes cell survival.Bcl-2The abnormally high expression of is closely related to the occurrence, development, and treatment resistance of various cancers, especially in follicular lymphoma and chronic lymphocytic leukemia, where gene translocation leading to overexpression is common. This protein is located in the outer membrane, nuclear membrane, endoplasmic reticulum membrane, and cytoplasm of mitochondria. target, aim at, address, focus on, in response toBcl-2In depth research is of great significance for understanding cellular homeostasis, tumor mechanisms, and developing novel anti-cancer therapies.

AbbVie AgencyTianjin Yiyuan Likang Biotechnology Co., LtdEstablished in2018Located in Tianjin Economic and Technological Development Zone. The company's product line covers multiple directions such as cell and gene therapy, immunology, molecular biology, and cell biology. It focuses on the sales of life science reagents, consumables, cells, instruments, and other products. The main brands it operates include:ThermoFisherTheSigmaTheQiagenTheEZBioscienceTheZYMO ResearchTheMedKooTheAbcamTheElabscienceTheGeneTexTheGentaurTheImmunologistTheInvitrogenTheinvivogenTheKerafastWait. We provide high-quality and cost-effective products, timely and effective services, and strive to become a high-quality supplier for life science and biotechnology enterprises.