Bax recombinant rabbit monoclonal antibody

1、 Basic Product Information

1. Product English Name:Bax Recombinant Rabbit Monoclonal Antibody

2. Product Chinese Name:BaxRecombinant rabbit monoclonal antibody

3. Product AliasBAX；BCL2L4；Apoptosis regulator BAX；Bcl-2-like protein 4；Bcl2-L-4；Bax-protein；BAXA；BCL2 associated X protein；membrane isoform alpha

4. Product Specification: Item NumberAWA12682

2、 Product specific parameters

1. Host: Rabbit

2. monoclonalorPolyclonal: Monoclonal

3. Clone number: not provided

4. Subtype:IgG

5. Reaction species: human, mouse, rat, goat, pig

6. Application: Protein Imprinting（WB）Immunohistochemistry (paraffin sections,IHC-P）Immunofluorescence Cytochemistry（IF-C）Immunofluorescence Histochemistry（IF-T）Immunoprecipitation（IP）Flow cytometry（FCM）

7. Immunogen: human sourceBaxproteinNend1-50Peptide synthesis based on amino acid sequence

8. Concentration:1.134 mg/mL

9. Form: Liquid

10. Purification process: Affinity chromatography purification

11. Storage solution: containing50%Glycerol0.5%Bovine serum albumin（BSA）And0.02%Sodium azide phosphate buffer solution（PBS）

12. Transportation conditions: Ice pack transportation

13. Recommended short-term storage time and conditions: After receiving the goods-20°CSave, stable within one year

14. Recommended long-term storage conditions:-20°CStore away from light, no need for packaging

3、 Product Details

This product is designed forBaxRecombinant rabbit monoclonal antibody for protein, item numberAWA12682The antibody is prepared using synthetic peptide immunogen and purified by affinity chromatography, which can specifically recognize endogenous proteinsBaxProtein. Excellent performance in various applications, including protein blotting (recommended dilution ratio)1:1000-1:10000）Immunohistochemistry (paraffin sections, recommended dilution ratio)1:100-1:500）Immunofluorescence (Cellular)/Organization, recommended dilution ratio1:50-1:500）Immunoprecipitation (recommended dilution ratio)1:100-1:300）And flow cytometry (recommended dilution ratio)1:50-1:200）. Experimental data shows that it can effectively detect a molecular weight of approximately in samples from various species such as humans, mice, and rats21 kDaThe target band has good specificity and low background.

4、 Target information

Bax（Bcl-2-associated X protein）Yes, it isBcl-2An important member of the protein family, as a pro apoptotic protein, plays a core regulatory role in the mitochondrial pathway of programmed cell death (apoptosis). In normal cells,BaxIt mainly exists in the cytoplasm in monomeric form. When cells receive apoptotic signals (such asDNAAfter injury and growth factor deprivation,BaxWill undergo conformational changes and transfer to the outer membrane of mitochondria, oligomerizing to form pores, leading to increased permeability of the outer membrane of mitochondria and promoting cytokine expressioncWait for the release of apoptotic factors into the cytoplasm, and then activate themcaspaseCascade reaction ultimately triggers cell apoptosis.BaxThe activity is influenced by other factorsBcl-2Family proteins (such as anti apoptotic proteins)Bcl-2TheBcl-xL, as well as pro apoptotic proteinsBidThe precise regulation of its expression level or functional abnormalities is closely related to various pathological processes such as tumorigenesis and neurodegenerative diseases. Therefore,BaxIt is a key target protein in the field of apoptosis research.

Bax recombinant rabbit monoclonal antibody AbbVie AgencyTianjin Yiyuan Likang Biotechnology Co., LtdEstablished in2018Located in Tianjin Economic and Technological Development Zone. The company's product line covers multiple directions such as cell and gene therapy, immunology, molecular biology, and cell biology. It focuses on the sales of life science reagents, consumables, cells, instruments, and other products. The main brands it operates include:ThermoFisherTheSigmaTheQiagenTheEZBioscienceTheZYMO ResearchTheMedKooTheAbcamTheElabscienceTheGeneTexTheGentaurTheImmunologistTheInvitrogenTheinvivogenTheKerafastWait. We provide high-quality and cost-effective products, timely and effective services, and strive to become a high-quality supplier for life science and biotechnology enterprises.