5020-87053 GL liquid chromatography column

5020-87053GLLiquid chromatography column

Specially designed to enhance the retention capacity of polar compounds, suitable for reverse phase high-performance liquid chromatography（HPLC）Analysis. Its core advantage lies in the use of high-purity spherical silica gel and optimizedC18Bonding technology can be used in high water phase and even100%Stable operation under aqueous and mobile phase conditions, effectively avoiding“Hydrophobic collapse”problem

Item Number‌：5020-87053

‌brand‌：GL Sciences(Technology), often used in the Chinese market“Shimadzu”Brand joint promotion

‌stationary phase‌：InertSustain AQ-C18(Octadecyl bonded phase)

‌matrix material‌High purity spherical silica gel (new type)ESSilicone)

‌particle size‌：‌5 µm‌

‌column length‌：‌50 mm‌

‌inner diameter‌：‌2.1 mm‌

‌specific surface area‌：350 m²/g

‌aperture‌：100（10 nm）

‌Micro pore volume‌：0.85 mL/g

‌End capped tail‌Yes, it is

‌carbon loading‌：‌13.0%‌

‌pHscope‌：‌1–10‌(Suitable for strong acidic and alkaline mobile phases)

‌USPserial number‌：L1, L96

‌Maximum pressure tolerance‌：20 MPa（200 bar）

‌Applicable mode‌Reverse phase liquid chromatography（Reversed Phase HPLC）

‌Application features‌Specially designed to enhance‌Retention ability of polar compounds‌Design, can be used in high water phase or even100%Stable operation under aqueous conditions, effectively avoiding“Hydrophobic collapse”problem

Core advantages and technological features

‌High polarity retention capability‌: Using specially designedC18Bonding phase, strict control of carbon chain spacing, even in‌High water phase or100%Water phase mobile phase‌Under certain conditions, strong polar compounds can still be effectively retained, avoiding traditional methodsC18Common pillars“Hydrophobic collapse”problem

‌Highly inert filler‌Based on high-purity spherical silica gel (new type)ESSilicone gel has few surface active sites and no significant adsorption of alkaline substances, which can be obtained‌Sharp and symmetrical peak shape‌Improve quantitative accuracy.

‌widepHtolerance‌: Can be inpH ‌1–10‌Stable operation within the range, suitable for strong acid or strong alkaline mobile phase systems, expanding the flexibility of method development.

‌Excellent inter batch reproducibility‌Produced under strict quality control, ensuring highly consistent retention time and separation efficiency between different batches, suitable for long-term stability research and method validation.

Typical application scenarios

‌Pharmaceutical Analysis‌Used for detecting polar metabolites, impurities, or degradation products in drugs, such as amino acids and organic acid compounds.

‌Biological sample analysis‌Suitable for the separation of polar small molecules in complex matrices such as plasma and urine, such as vitaminsBEthnicity, nucleotides, etc.

‌Environment and Food Safety‌Can be used for residual detection of polar pollutants in water and food additives (such as sweeteners and preservatives).

‌LC-MSPre processing for combined use‌Due to its stable performance under high water phase conditions, it helps to improve the ionization efficiency and signal intensity of mass spectrometry.

This chromatographic column is particularly suitable for the needs‌High selectivity and high reproducibility‌The analysis task is an ideal choice for developing detection methods for polar components in complex samples.