Azide disulfide succinimide ester

Common names:Azide disulfide succinimide ester

Description:Azide disulfide succinimide esterAzide Disulfide Succinimide Ester is a chemical molecule with multiple functional groups, commonly used in biochemical and medicinal chemistry research, particularly in molecular linking, labeling, and drug delivery systems.

This molecule consists of the following main components:

Azide: Azide is a highly reactive chemical group widely used in click chemistry. The diazo group can react rapidly and efficiently with cyclic triazole (Alkyne) groups containing triple bonds, forming stable covalent bonds. In biomarkers and drug delivery, azide groups are often used to bind with other molecules or carriers for molecular linkage.

Disulfide Bond: Disulfide bonds are formed by covalently connecting two sulfur atoms and are typically present in the folded structure of protein molecules. Disulfide bonds are sensitive to reduction and can be broken under specific reduction conditions. Therefore, disulfide bonds play an important role in drug delivery systems, especially in targeted drug release. In the reducing environment inside the cell, disulfide bonds can be cleaved to release drugs or active ingredients.

Succinimide Ester: The succinimide ester group is a common active ester that can react with amino containing (- NH ₂) molecules to form stable amide bonds. It is commonly used in drug synthesis, antibody labeling, and molecular cross-linking reactions. Through succinimide ester, drugs, antibodies, or other biomolecules can be linked to target molecules to achieve targeted therapy or molecular recognition.

Application:

Drug delivery system:Azide disulfide succinimide esterIt has a wide range of applications in drug delivery, especially in targeted drug release. The reduction sensitivity of disulfide bonds allows drugs to be effectively released in specific cellular or tissue environments, while azide groups can bind to other molecules or carriers through click chemistry.

Molecular labeling and crosslinking: Through the reactivity of succinimide ester groups,Azide disulfide succinimide esterIt can be used to link drugs, proteins, antibodies, or other biomolecules with specific labeling molecules for applications such as molecular labeling, diagnosis, and imaging.

Stable connections between molecules:Azide disulfide succinimide esterIt can be used to establish stable covalent connections between molecules, especially in the cross-linking and combination processes of biomolecules such as proteins, nucleic acids, and drugs.

In summary,Azide disulfide succinimide esterIt is a multifunctional molecule with high reactivity that can be used in fields such as molecular labeling, drug delivery, targeted therapy, and molecular cross-linking. It is particularly suitable for drug release and biomolecule combination that require response in a reducing environment.

Purity: 90%+

Packaging: Bottled!

Origin: Xi'an

Purpose: Scientific research!

Specification: mg/g

Kind reminder: For scientific research only, not for human experiments!

About Us: Xi'an Huirui Biotechnology Co., Ltd. is a high-tech enterprise that integrates research and development, production, and sales of high-quality scientific research reagents. Its main business directions include: synthesis of phospholipids, polymer polyethylene glycol derivatives, block copolymers, paramagnetic/superparamagnetic nanoparticles, nano gold and nano gold rods, near-infrared fluorescent dyes, reactive fluorescent dyes, fluorescently labeled dextran BSA and streptavidin, protein crosslinkers, small molecule PEG derivatives, click chemistry products, dendritic polymers, cyclodextrin derivatives, macrocyclic ligands, fluorescent quantum dots, hyaluronic acid derivatives, graphene or graphene oxide, carbon nanotubes, fullerenes, etc. It also provides various customized product services!

Related recommendations:

cas:98627-69-1，1,3-Bis-aminooxy propane

cas:99208-90-9，Alkynyl Palmitic Acid

DBCO-C4-Val-Cit-PABC-PNP

DBCO-PEG3-SS-NHS Ester

DBCO-PEG4-AcBu-Calicheamicin

DBCO-PEG4-Val-Ala-PAB-PNP， Dibenzocyclooctyne tetrapolyethylene glycol VAL-ALA-PAB-PNP

DBCO-PEG4-VA-PAB-EDA-N-Ac-Calicheamicin

Dbco-peg 4 -vc-pab (PEG 2) - duowaycin

DBCO-PEG4-VC-PAB-DMAE-PNU159682 cas:2259318-56-2

DBCO-PEG4-vc-PAB-MMAE

DBCO-Val-Cit-PAB-MMAE， Dibenzocyclooctylene-VAL-CIT-PAB-MMAE

DBM-MMAF