Bis (N-hydroxysuccinimide) phthalate

Description:

Bis (N-hydroxysuccinimide) phthalate（Azelaic acid bis(N-Hydroxysuccinimide ester)）It is a chemical molecule with two NHS ester groups, commonly used in chemical synthesis, biochemical research, as well as molecular crosslinking and labeling reactions. It is a molecule composed of Azelaic acid and two N-Hydroxysuccinimide (NHS) ester groups.

Structure and composition:

1. Azelaic acidSuccinic acid is a saturated dicarboxylic acid containing 9 carbon atoms (C9H16O4). It has two carboxyl groups (- COOH) and is a common fatty acid. Succinic acid is commonly used in the synthesis of chemicals such as plastics, coatings, surfactants, and is also widely used in the pharmaceutical and cosmetics industries, especially in skin care. Its two carboxyl groups provide reactivity for covalent bonding with other molecules.

2. NHS酯 （N-Hydroxysuccinimide Ester）NHS ester is an active ester containing N-hydroxysuccinimide, which can react with amino (- NH ₂) groups to form stable amide bonds. In molecular cross-linking, labeling, and drug synthesis, NHS ester groups are often used to connect with biomolecules such as proteins, antibodies, enzymes, etc.

Application:

1. Molecular cross-linking and labelingBis (NHS ester) is commonly used in molecular cross-linking reactions, especially in biochemical research, to connect different biomolecules (such as proteins, antibodies, drugs, nucleic acids, etc.). By reacting the compound with the target molecule, precise molecular labeling or construction of molecular complexes can be achieved.

2. Drug synthesis and deliveryBis (NHS ester) can be used as a linking group in drug delivery systems to optimize drug release performance or targeting by linking drugs or other molecules. It can form covalent bonds with drugs or carriers containing amino groups, achieving targeted delivery.

3. Immunology and Molecular Biology ResearchIn immunological research, bis (NHS ester) succinate can be used to link antibodies, antigens, or other biomarkers for molecular detection or cell tracking. In molecular biology, this compound can be used to construct probes or other biomarker systems.

4. Surface modification of biomaterialsBy using succinic acid bis (NHS ester) on the surface of biomaterials, the biocompatibility of the material can be enhanced or specific functional groups (such as proteins, antibodies, or enzymes) can be immobilized on the material surface. This has wide applications in the fields of biosensors, medical devices, and tissue engineering.

Summary:

Bis (NHS ester) succinateIt is a functional chemical reagent mainly used in fields such as molecular cross-linking, drug delivery, and biomarkers. The succinic acid backbone provides covalent binding sites with other molecules, while the NHS ester group provides efficient reactivity with amino groups, making it a useful tool in organic synthesis, drug development, and biochemical research.

Common names:Bis (N-hydroxysuccinimide) phthalate

Purity: 90%+

Packaging: Bottled!

Origin: Xi'an

Purpose: Scientific research!

Specification: mg/g

Kind reminder: For scientific research only, not for human experiments!

About Us: Xi'an Huirui Biotechnology Co., Ltd. is a high-tech enterprise that integrates research and development, production, and sales of high-quality scientific research reagents. Its main business directions include: synthesis of phospholipids, polymer polyethylene glycol derivatives, block copolymers, paramagnetic/superparamagnetic nanoparticles, nano gold and nano gold rods, near-infrared fluorescent dyes, reactive fluorescent dyes, fluorescently labeled dextran BSA and streptavidin, protein crosslinkers, small molecule PEG derivatives, click chemistry products, dendritic polymers, cyclodextrin derivatives, macrocyclic ligands, fluorescent quantum dots, hyaluronic acid derivatives, graphene or graphene oxide, carbon nanotubes, fullerenes, etc. It also provides various customized product services!

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