Corning Matrigel Matrix Adhesive 354248

1、 CorningMatrigelMatrigel354248Product Introduction

Product core features:GFRWan without phenol redbeautycombine

Corning Matrix Adhesive 354248 Originating from proteins rich in extracellular matrixEHS（Engelbreth-Holm-Swarm）Mouse sarcoma. Compared to the standard version of Corning matrix adhesive, this product has undergone targeted improvements to meet higher-level experimental requirements.

Reduced growth factors（GFR）Design:

Ordinary matrix adhesives contain endogenous growth factors, such as epidermal growth factor（EGF）Platelet derived growth factor（PDGF）Wait, this may interfere with researchers' experimental observations of specific signaling pathways. Corning Matrix Adhesive354248 The vast majority of endogenous growth factors were removed through physical adsorption. This feature enables researchers to fully control the types and concentrations of growth factors in the culture medium, thereby more accurately studying the effects of specific factors on cell proliferation and differentiation, avoiding interference from background signals.

Phenol free Red Formula:

Phenol red as a typepHIndicator has an indicative function in conventional culture, but it may cause interference in certain specific physiological and biochemical tests. Corning Matrix Adhesive354248 Removing the phenol red component not only eliminates the potential weak impact of phenol red on cellular metabolism, but more importantly, it greatly reduces the background fluorescence signal. This makes the matrix gel an ideal substrate material for high-sensitivity detection such as fluorescence microscopy observation, flow cytometry analysis, and laser confocal imaging.

two、 Core application areas

With its high purity and low interference properties, Corning matrix adhesive 354248 It has a wide range of applications in cutting-edge biological research.

1. Human embryonic stem cells andiPSCsCultivation:

In human pluripotent stem cells（hPSCs）In undifferentiated culture, interference from external signals may lead to spontaneous differentiation of cells. Corning Matrix Adhesive354248 Providing a culture surface with clearer chemical composition and cleaner background helps maintain the stemness of stem cells and genome stability.

2. Organoids and3DSpherical cultivation:

The core of organoid technology lies in simulating the microenvironment of internal organs. utilize Corning Matrix Adhesive354248 Wrapping stem cells or progenitor cells can induce their self-assembly into micro organs with specific structures and functions. Its phenol red free property ensures clear real-time fluorescence observation of the internal development of organoids during long-term cultivation.

3. Angiogenesis detection（Angiogenesis Assay）：

Researchers often use human umbilical vein endothelial cells（HUVEC）Forming tubular structures on matrix gel to evaluate the activity of pro angiogenic or anti angiogenic factors.GFRThe characteristics ensure that the observed angiogenic effects are entirely caused by the factors added in the experiment, rather than the endogenous factors carried by the matrix gel itself.

4. In vivo tumor xenograft:

Corning Matrix Adhesive 354248 Often mixed with tumor cells and inoculated into immunodeficient mice (such as subcutaneous inoculation), it can significantly increase the tumorigenic rate of tumor cells and form a xenograft model that is closer to the pathological characteristics of human tumors.

IIIcorningList of Matrix Adhesive Models

CorningMatrixL matrix adhesive354248Tianjin Yiyuan Likang Biotechnology Co., Ltd., established in2018Located in Tianjin Economic and Technological Development Zone. The company's product line involves cell and gene therapy, immunology, molecular biology We specialize in sales of life science reagents, consumables, cells, instruments, and other products in multiple fields such as cell biology. Our main brands include:ThermoFisherTheSigmaTheQiagenTheEZBioscienceTheZYMO ResearchTheMedKooTheAbcamTheElabscienceTheGeneTexTheGentaurTheImmunologistTheInvitrogenTheinvivogenTheKerafastWait. We provide high-quality and cost-effective products, timely and effective services, and strive to become a high-quality supplier for life science and biotechnology enterprises.