Recombinant Anti Stone H3 antibody EPR16987

1、 Basic Product Information

1. Product English Name:Anti-Histone H3 antibody [EPR16987] - Nuclear Marker and ChIP Grade

2. Product Chinese Name:Recombinant Anti Stone H3 antibody EPR16987-Nuclear labeling and chromatin immunoprecipitation grade

3. Product AliasHistone H3 Antibody, H3 Antibody

4. Product Specification: Item NumberAB176842Specific specifications (such as volume)/The concentration needs to be determined based on the actual ordering information.

2、 Product specific parameters

1. Host: Rabbit

2. monoclonalorPolyclonal: Monoclonal

3. Clone number:EPR16987

4. Subtype:IgG

5. Reaction species: human, mouse, rat, fruit fly, brewing yeast, fission yeast

6. Application: Verified to be suitable forWestern Blot (WB)Immunocytochemistry/Immunofluorescence(ICC/IF)Chromatin immunoprecipitation(ChIP)Flow cytometry (intracellular)(Flow Cyt (Intra))Peptide array(PepArr)Immunohistochemistry (paraffin sections)(IHC-P)

7. Immunogen: The exact sequence of the immunogen that produces the antibody is proprietary information.

8. Concentration: Specific concentration information needs to refer to the product batch analysis certificate.

9. Form: Liquid

10. Purification process:Protein Aprotein purification

11. Storage solution: containing0.05% BSA、40%Glycerol'sPBSSolution and add0.01%Sodium azide is used as a preservative.

12. Transportation conditions: Can be transported at room temperature.

13. Recommended short-term storage time:1-2week

14. Recommended short-term storage conditions:4°C

15. Recommended long-term storage conditions:-20°CIt is recommended to pack and store separately to avoid repeated freezing and thawing.

IIIRecombinant Anti Stone H3 antibody EPR16987Product Details

This product is a rabbit derived recombinant monoclonal antibody, clone numberEPR16987Specific recognition of histonesH3The antibody has been validated on multiple technical platforms and has broad application compatibility, includingWestern BlotImmunofluorescence, chromatin immunoprecipitation, and flow cytometry are suitable for studying various model organisms from yeast to mammals. Its specificity has been demonstrated through gene knockout cell lines（H3C1Knocked outHAP1Cells)Western BlotExperimental confirmation. This antibody is from2014Since its publication, it has been surpassed70The cited peer-reviewed literature confirms its reliability and wide application value in research fields such as chromatin biology and epigenetics. The use of recombinant antibody technology ensures high inter batch consistency and long-term stable supply of the product.

4、 Target information

histoneH3It is an important member of the core histone family, andH2ATheH2BTheH4The core octamer that collectively constitutes the nucleosome is the fundamental structural unit for chromatin assembly. Its main function is to package and compressDNAForming chromatin fibers to regulate the genomeDNAAccessibility. histoneH3ofNThere are various post-translational modifications that can occur at the end and tail, such as methylation, acetylation, phosphorylation, etc. These modifications are related to“histone code”Jointly dynamically regulating chromatin status in gene transcription activation and silencingDNADamage repairDNAPlays a critical role in core cellular processes such as replication and maintenance of chromosome stability. Therefore, regarding histonesH3Antibodies are essential tools for studying epigenetic regulatory mechanisms.

5、 Abcam represents Tianjin Yiyuan Likang Biotechnology Co., Ltd., which is a product and technical service provider specializing in the field of life sciences. We are committed to providing high-quality reagents, consumables, and technical solutions for researchers.

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