Huakan bioreactor has good operational flexibility and can adapt to various types of biological reaction processes, whether it is microbial culture or cell culture. It has been widely used in various fields such as biomedicine and food fermentation. By optimizing reaction conditions and enhancing mass transfer efficiency, it has improved production efficiency and product quality, and shortened production cycles. The use of bioreactors can significantly save the cost of building factories and purchasing equipment, simplify complex production processes, reduce production costs, and reduce environmental pollution compared to traditional production processes. This is because it can efficiently carry out biotransformation in a closed system, reduce waste emissions, and has a compact design that effectively saves space resources in laboratories or production workshops.

Measurement steps of Huakan bioreactor:

1. Determination of oxygen transfer coefficient (kLa)

-Dissolved oxygen concentration calibration: ensures the accuracy of measuring equipment and provides a reliable data basis for subsequent calculations.

-Gas flow accuracy verification: Adjust the gas flow meter of the reactor, select one or more gas flow rates within the user's commonly used range as measurement points, measure continuously for 3 times, record the measured value Qi each time, and calculate the average value.

-The effect of stirring speed on kLa: Changing the stirring speed and observing how it affects the transfer efficiency of oxygen in the liquid.

-The influence of temperature on oxygen transfer efficiency: Conduct tests under different temperature conditions to analyze the relationship between temperature changes and oxygen transfer.

-Pressure dependent testing: Investigating whether changes in pressure within the system will affect oxygen transfer efficiency.

-Analysis of pH interference on kLa: Study the changes in oxygen solubility and transfer rate under different pH environments.

-Assessment of the impact of culture medium components: Repeat experiments using culture media containing different nutritional components to understand their effects on oxygen transfer.

-Measurement of Bubble Size Distribution: Using specialized instruments to determine the range of bubble sizes generated, optimizing ventilation methods to improve mass transfer efficiency.

-Calculation of gas-liquid interface area: Based on the above parameters, the effective contact surface area is calculated to further quantify the reaction efficiency.

2. Testing of other performance indicators

-Structural integrity check: Confirm that the physical structure of the equipment is free from damage or defects.

-Sealing performance test: Ensure that the reactor can effectively prevent leakage and maintain the stability of the internal environment.

-Corrosion resistance assessment: Testing the corrosion resistance ability after exposure to specific chemical substances.

-Temperature tolerance test: Verify whether the equipment can operate normally within the set temperature range without failure.

-Fluid uniformity analysis: Ensure that the materials in the reactor are thoroughly mixed and evenly distributed.