Peking University School of Medicine purchases ZJ-3 precision D33 tester and PZT-JH30/3 piezoelectric composite polarization device

Piezoelectric bioceramics is a type of piezoelectric ceramic material used in the biomedical field, which includesbarium titanateLead zirconate titanate（PZT）Waiting for perovskite type ceramics,lithium niobate（LiNbO3）Single crystal materials andPolymer composite materials, throughpiezoelectric effectRealize the mutual conversion of mechanical energy and electrical energy This material is mainly used as a human body information detection sensor, including cardiac catheterization micropressure devices, ultrasound therapy equipment, and wearable motion monitoring devices. It can also be used for dental antibacterial filling and implantable ultrasound energy harvesting systems .

After discovering the piezoelectric properties of materials such as crystals in the late 19th century,1940eraBarium titanate piezoelectric ceramicComing out,1960The development of niobate ceramics such as lithium niobate,1970Lead lanthanum zirconate titanate was developed in the era（PLZT）Transparent ceramics .21Since the turn of the century, hot-Electric driven aerosol printing technology realizes glycine/PVPManufacturing of composite piezoelectric thin films with a piezoelectric coefficient of11.2 pm/VApplied to transient cardiac pacemakers Barium titanate/Tricalcium phosphate（BTTCP）Composite ceramics have been proven to have biological activity in promoting bone cell growth through porous structure design .

The natural piezoelectric effect of bone tissue generates local electrical signals through mechanical stimulation, regulating the behavior of bone cells and providing a theoretical basis for the application of piezoelectric materials in orthopedic medicine. Excellent piezoelectric materials demonstrate great potential in bone tissue repair, cartilage regeneration, inflammation regulation, and health monitoring through the mechanism of electromechanical coupling.

The core mechanism of piezoelectric materials is their unique electromechanical coupling effect, which activates the electrobiological response of bone cells through the local electric field generated by mechanical stimulation. Specifically, it includes: activation of voltage sensitive ion channels (such as VGCC, Piezo1, TRPV4), triggering calcium ion influx, further activating Wnt/β - catenin, PI3K/Akt and other signaling pathways, promoting osteoblast differentiation and mineralization; The electric field regulates cytoskeleton reorganization through the focal adhesion complex (FAK integrin pathway), enhances cell adhesion and migration, and promotes bone tissue regeneration; In addition, electrical stimulation can regulate signaling pathways such as TGF - β and Notch, promoting intercellular communication and differentiation processes. At the same time, piezoelectric materials induce macrophages to polarize towards M2, inhibit inflammatory reactions, optimize the bone repair microenvironment, and comprehensively regulate the regeneration and repair of bone tissue.

In orthopedic medicine, piezoelectric materials are widely used in fields such as bone tissue repair, health monitoring, and inflammation regulation. In terms of bone tissue repair, inorganic piezoelectric materials (such as BaTiO3, ZnO, PZT) exhibit excellent electric field generation ability due to their high voltage constant, but their clinical applications are limited by biocompatibility and mechanical brittleness. Organic materials such as PLLA and PVDF have flexibility, biodegradability, and good tissue compatibility, making them suitable for development as implantable piezoelectric scaffolds. In addition, organic-inorganic composite materials (such as PVDF/BaTiO3, PLLA/ZnO) enhance material properties through electromechanical coupling, achieving optimization of mechanical strength and biocompatibility, and are widely used in bone defect repair, cartilage regeneration, and inflammation relief.

In terms of health monitoring, implantable piezoelectric sensors provide accurate data support for fracture healing, spinal fusion, and osteoporosis treatment by real-time monitoring of bone density, stress distribution, and healing process. Meanwhile, wearable piezoelectric devices such as flexible sensors, insoles, and patches are used for motion monitoring, gait analysis, and physiological signal detection, which can help achieve early diagnosis and evaluation of chronic bone diseases such as osteoarthritis and osteoporosis.

In inflammation regulation and anti infection therapy, piezoelectric catalytic materials trigger local reactive oxygen species (ROS) production through mechanical energy, effectively killing bacteria and eliminating inflammatory factors, providing a non pharmacological and non-invasive treatment option for infectious bone diseases. In addition, combined with ultrasound stimulation, piezoelectric scaffolds can activate local electric fields, accelerate bone tissue healing and cartilage regeneration, and reduce the recovery period of patients.

In summary, piezoelectric materials, through their unique bio electromechanical coupling mechanism, can activate bone cell signaling pathways, regulate the immune microenvironment, and promote bone tissue regeneration, demonstrating broad application prospects. Future research should further optimize the long-term stability, mechanical strength, and biosafety of materials, combined with 3D printing and intelligent manufacturing technology, to achieve personalized and precise treatment plans, and promote the clinical translation and application of piezoelectric materials in the field of orthopedic medicine.

ZJ-3 Precision Piezoelectric d33 Tester

1、 Product Introduction:

The ZJ-3 piezoelectric tester (static pressure coefficient d33 measuring instrument) is a specialized instrument designed to measure the d33 constant of piezoelectric materials. It can be used to measure piezoelectric ceramics with large piezoelectric constants, piezoelectric single crystals and polymer materials with small piezoelectric constants, and PVDF thin film piezoelectric samples. ZJ-4 extends the D31 block, D31 thin film stretching fixture, D15 strip fixture, and D15 round tube fixture. This instrument is used in the production, application, and research departments of piezoelectric materials and piezoelectric components.

2、 Reference standards:
GB3389.4-82 "Testing Methods for Properties of Piezoelectric Ceramic Materials - Static Test of Longitudinal Piezoelectric Strain Constant d33"

GB/T3389.5-1995 "Testing methods for properties of piezoelectric ceramic materials - Circular thickness expansion vibration mode"GB000?

Tj1.1/T3389.4-1982 "Testing Method for Properties of Piezoelectric Ceramic Materials - Longitudinal Length Expansion Vibration Mode of Column"

GB/T 3389.7-1986 "Test Methods for Properties of Piezoelectric Ceramic Materials - Test for Strong Field Dielectric Properties"
GB/T3389.8-1986 "Testing Methods for Properties of Piezoelectric Ceramic Materials - Test for Pyroelectric Coefficient

3、 Main functions of the product:

Measure the d33 constant of piezoelectric materials

Measurement of piezoelectric ceramics with large piezoelectric constants

Piezoelectric single crystals and piezoelectric polymer materials for measuring small piezoelectric constants

Measure the equivalent piezoelectric d'33 constant of arbitrary orientation piezoelectric single crystals and certain piezoelectric devices

Thin film PVDF piezoelectric coefficient D33 test

Eight sets of fixtures including D31 block, D31 film stretching fixture, D15 strip fixture, D15 round tube fixture, etc4、 Main technical indicators

D33 measurement range:

1 gear: 20 to 2000pC/N with an extension of 10000PC/N

0.1 gear: 2 to 400pC/N.

Can be used in conjunction with PZT-JH10/4/8/12 piezoelectric polarization device

Can be used in conjunction with ZJ-D33-YP15 voltage chip machine
Error: * 1 gear: ± 2% ± 1 digit, when d33 is between 100 and 4000pC/N;

Measurement calibration standard sample size: 18mm * 0.8mm, aging time: 2-3 years (one of the important criteria for evaluating the accuracy performance of piezoelectric testers)

Provide piezoelectric film standard sheet: 20 * 20MM

Voltage protection: discharge protection function

D31 block, D31 film stretching fixture, D15 strip fixture, D15 round tube fixtureD31Block fixture, film stretching fixture (new function),Coplanar electrode function (new)

± 5% ± 1 digit, when d33 is between 10 and 200pC/N;
0.1 gear: ± 2% ± 1 digit (when d33 is between 10 and 200pC/N)
± 5% ± 1 digit, when d33 is between 10 and 20pC/N.

Resolution: × 1 gear: 1 pC/N; 0.1 gear: 0.1 pC/N.
Size: Force application device: Φ 110 × 140mm; Instrument body: 240 × 200 × 80mm.
Weight: Force application device: approximately 4 kilograms;
Instrument body: 2 kilograms.
Power supply: 220V, 50Hz, 20W.

PZT-FJH30 /3Vacuum, air,Atmosphere, silicone oil piezoelectric ceramic high-voltage polarization device（30KVThe following piezoelectric ceramics and piezoelectric films1-3Sample pieces)Mainly used for polarization treatment of piezoelectric ceramics or other piezoelectric materials below 30KV, widely used in universities and research and production units engaged in piezoelectric material research or production.

This piezoelectric testing device is equipped with multiple polarization fractions such as air, vacuum, and atmosphere. It can polarize 1-3 samples simultaneously or separately in an oil bath, and can test anisotropic material components such as square, circular, and ring, and polarize different propertiesPiezoelectric thin film material. It is an important auxiliary tool for current piezoelectric research in China.

Key Features:

1. Capable of polarization simultaneously1-3Piezoelectric sample or piezoelectric thin film sample

2. Safe and reliable, fast temperature compensation, high temperature control accuracy

3. Each circuit has a cut-off protection function when the leakage current exceeds the specified value, which does not affect the polarization of other samples. Other circuits can complete polarization according to normal polarization time.

4Provide standard polarized film samples:3piece (Two big and one small)

5Provide test sample film:3piece （ Two big and one small)

6. It is possible to observe the changes and curves of polarization current, voltage, and temperature.

Main technical parameters:

1. Any sample size of 3-40mm, whether it is a square or circular specimen, can be clampedPiezoelectric thin film specimen

2. Provide standard polarizing film samples: 3 pieces

3. Provide test sample film: 3 pieces

4Working power supply:AC220V 50/60HZ

5Rated power:2.0kw

6. Polarization modes of piezoelectric materials: vacuum, air, atmosphere, silicone oil, etc10Multiple polarization modes

7Total current:10mA

8Cut off current in each circuit:0.5mA

9Timing:1-99min±5%Any setting

10Heating element High quality resistance wire

11、1Number of test samples for secondary testing:Loadable1-3Sample piece

12Rated temperature ：≤180℃

13Temperature ：300℃

14Temperature control method Intelligent constant temperature control

15Sample pieces The sample size is3-40mmSquare or circular specimens or piezoelectric thin film specimens

16External dimensions : Width872high466deep360（mm)

17Can be matchedZJ-3andZJ-6Use a piezoelectric tester for testing purposes