Tissue engineering microfluidic channel glass slide

Tissue engineering microfluidic channel glass slide80236 80236-90 80236-120

µ - Slide tissue engineering slide is a microfluidic channel slide designed specifically for tissue modeling and organ-on-a-Chip applications.

A platform for building 3D microenvironments or performing light induced 2D/3D microfabrication and patterning

Equipped with standard Luer interface for fluid access, seamlessly integrating pump systems

The bottom is a high-quality optical grade # 1.5 polymer cover glass, suitable for high-resolution imaging

Ibidi microscopy imaging products:Tissue engineering microfluidic channel glass slideProvide different bottom treatments and packaging specifications

Application fields:µ - Glide tissue engineering microfluidic slides provide a flexible solution for designing and studying complex 2D and 3D tissue models under controlled fluid conditions.

Tissue and organ chip model:

• Customized 3D junction µ - Slide structure: use photocrosslinking hydrogels (such as GelMA, PEG-DA, collagen or hyaluronic acid) to construct microchannels, bifurcated structures or flow barriers through photoinduced polymerization.

• Tissue and organ models: Construct microscopic tissue models (such as vascular networks or tumor microenvironments) for studying cell behavior, drug effects, or tissue regeneration.

• Construction of topological surfaces: Simulating the tissue microenvironment by replicating the structure and hardness of natural tissues.

Microfluidic technology:

• High precision microfluidics: seamlessly integrate the ibidi pump system to precisely control the perfusion of microchannels and hydrogels.

Simulate interstitial flow: reproduce the flow pattern of body fluids in tissues and explore the mechanisms of cell perception and response to shear stress.

Gradient formation: Generate concentration gradients in a 3D environment through dynamic perfusion.

Dynamic microenvironment: Using controlled perfusion to maintain cell viability and simulate changing physiological conditions.

Microscopic imaging technology:

Suitable for cell monitoring using bright field, phase contrast, and wide field fluorescence microscopes for inverted microscopes.

Long term live cell imaging and delayed research.

Confocal microscopy, two-photon microscopy, FRAP, FRET, FLIM, and LSFM.

Specification parameters:

Technical features:

Precision, quality, and biocompatibility

Microfluidic channel slides have two working areas with parallel channels on each side

# 1.5 ibidi polymer cover glass with optical quality

• Compatible with fluid photocrosslinked hydrogels or extracellular matrix

• Compatible with staining and fixing solutions

• Compatible with immersion in oil

Made of non-toxic and biocompatible materials

• Aseptic independent packaging

• Compatible with high-resolution fluorescence microscopes

• Better performance when used in conjunction with the ibidi Micro Illumination System

• Standard Ruhr interface: compatible with various fluids and infusion devices (such as the ibidi fluid shear force system)

Product Version

• Also available: Sticky Slide Tissue Engineering tissue engineering adhesive based microfluidic slides for unlimited access to the workspace (suitable for applications such as additive 3D printing)

How does µ - Slide tissue engineering microfluidic slide work?

Working principle of µ - Slide tissue engineering microfluidic slides

This slide provides a flexible platform for designing and studying complex 2D and 3D tissue models under controlled fluid conditions. This slide is made up of oneThe workspace is composed of parallel channels on both sides. The work area can be filled and constructed with light crosslinked hydrogels (such as GelMA, PEG-DA, collagen or hyaluronic acid).

These hydrogels can be aggregated to form specific patterns through the ibidi Micro Illumination System or similar equipment. The slide design can be seamlessly integrated with the ibidi fluid shear system to achieve controllable perfusion, simulate physiological blood flow and nutrient delivery.

What are the applications of µ - Glide tissue engineering microfluidic slides in?

µ - Glide tissue engineering microfluidic slides are designed specifically for advanced 2D and 3D cell culture experiments that require simulation of real tissue environments and fluid control, such as:

• Tissue and organ modeling

• Flow and perfusion research

• Gradient formation

Can photolithography or microstructure preparation be performed on µ - Glide tissue engineering microfluidic slides?

Okay. For example, in conjunction with the ibidi Micro Illumination System, cell attachment, growth, and migration areas can be defined through photolithography or microstructure techniques. This technology can construct highly controllable tissue structures, including directionally arranged neurons, patterned co culture systems, and wound healing models. In addition, to simulate the natural tissue environment and guide cell behavior, surface topographies and protein patterns can also be generated.

Structural Example

The work area and side channels can be structured using photo crosslinked hydrogels to determine the location of cell/tissue models and fluid channels

Is µ - Glide tissue engineering microfluidic slide compatible with the ibidi pump system?

Compatible. µ - Glide tissue engineering microfluidic slides can be easily connected to pump systems such as the ibidi pump system through a Ruhr adapter, achieving precise control of perfusion rate and flow field distribution. This configuration can simulate physiological conditions such as blood flow, interstitial flow, or dynamic shear stress, and supports parallel perfusion of channels to achieve complex flow field scenarios.

Example of Flow Settings

According to the structural characteristics, multiple infusion methods can be used, including single channel infusion and multi-channel parallel infusion.

Is µ - Glide tissue engineering microfluidic slide suitable for live cell imaging?

Applicable. This slide has a high optical quality bottom, making it ideal for excellent imaging in wide field, confocal, or live cell microscopes. When used in conjunction with ibidi Stage Top Incubators or other incubators, it can maintain physiological conditions.

Does the use of µ - Glide tissue engineering microfluidic slides require the installation of an ibidi micro lithography irradiation system?

It's not necessary. You can directly fill hydrogel or stent without any structure; Alternatively, you can use the ibidi Micro lithography illumination systemIllumination System or other light induced techniques are used for 2D or 3D light structuring.

Application Examples

Stitching phase difference image of 200 μ m PEG-NB hydrogel column created in ibidi µ - Slide tissue engineering microfluidic slide