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TNFAIP3 monoclonal antibody

NegotiableUpdate on 05/06
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Overview

TNFAIP3(Tumor Necrosis Factor Alpha-Induced Protein 3), Also known as A20 protein, it is an important ubiquitin editing enzyme that plays a critical role in regulating immune responses, inflammatory signaling pathways, and cell apoptosis. TNFAIP3 helps maintain immune homeostasis and prevent excessive inflammatory response by negatively regulating the NF - κ B signaling pathway. TNFAIP3 monoclonal antibody

Product Details

1、 Product Description

This product is a highly specific and affinity productMouse sourceTNFAIP3 monoclonal antibodyThis antibody is prepared by using a recombinant human TNFAIP3 protein fragment as an immunogen and can specifically recognize endogenous TNFAIP3 protein.

TNFAIP3, Also known asA20, is a crucialNegative regulatory proteinIt plays a crucial role in the NF - κ B signaling pathway and cell apoptosis. It inhibits NF - κ B activation induced by various factors such as TNF, IL-1, and LPS through its deubiquitinase activity, and is an important hub molecule connecting innate and acquired immunity. This product provides a reliable detection tool for studying its role in inflammation, autoimmune diseases, and cancer.

2、 Product Features

  • High specificity:Verified by flow cytometry, it can specifically recognize TNFAIP3/A20 without significant non-specific binding.

  • High sensitivity:An endogenous TNFAIP3 protein band of approximately 90 kDa was clearly detected in Western Blot experiments.

  • Strict verification:Each batch of products has undergone multiple application tests such as WB and IP to ensure stable and reliable performance.

  • Multiple applications:Through experimental verification, it is suitable for various conventional applications such as Western Blot, immunoprecipitation, immunofluorescence, and immunohistochemistry.

3、 Product nature

  • Antibody source:mouse

  • Antibody type:monoclonal antibody

  • Immunogen:Recombinant human TNFAIP3 protein fragment

  • Reactivity:Human, mouse, rat

  • Clone number:[Please fill in the actual clone number, for example: A20-1A5]

  • Storage buffer solution:PBS (pH 7.4), 0.02% sodium azide, 50% glycerol

  • Storage conditions:-Stored at 20 ° C, valid for one year. Avoid repeated freezing and thawing.

4、 Application information (recommended dilution ratio)

  • Western Blot (WB): 1:1000

  • Immunoprecipitation (IP): 1:50

  • Immunofluorescence (IF/ICC): 1:200

  • Immunohistochemistry (IHC): 1:150

Attention: The optimal dilution ratio may vary depending on experimental conditions, and it is recommended that users optimize it according to the specific experimental system.

5、 Precautions

  1. Please centrifuge briefly before use to avoid loss of solution and inaccurate concentration.

  2. When using the first Chi, it is recommended to conduct a gradient dilution pre experiment to determine the optimal concentration for use.

  3. This product is only for professional researchers and cannot be used for diagnosis or treatment.


We are committed to providing you with high-quality research toolsTNFAIP3 monoclonal antibodyIt is your ideal choice for exploring immune regulation, inflammatory response, and cancer biology.


The above information is for reference only. Please refer to the instruction manual for details.