Second hand Agilent liquid chromatography-mass spectrometry LC-M1200-6410

Second hand Agilent liquid chromatography-mass spectrometry LC-M1200-6410Introduction:

The Agilent 6410 MS is equipped with Agilent's newly developed jet stream ion focusing ion source, which elevates the sensitivity of mass spectrometry detection of trace components in complex matrices to a new level of similar instruments in the industry. Triple quadrupole mass spectrometer has been widely used in various fields such as food safety, environmental analysis, pharmacokinetics research, metabolite identification, impurity analysis, etc; Meanwhile, in proteomics and metabolomics research, triple quadrupole mass spectrometry is commonly used for method and target substance validation.

Second hand Agilent liquid chromatography-mass spectrometry LC-M1200-6410Key Features:

1. Sensitivity

Jet flow ion focusing ionization technology increases the atomization temperature and electric field density, significantly improving ionization efficiency and effectively shielding substrate interference; In addition, under the action of high-speed sheath airflow, the ion cloud density significantly increases (ion focusing), thereby improving the efficiency of mass spectrometry sampling; The advancement of these technologies has improved the sensitivity of mass spectrometry detection through ion generation and transport processes; Meanwhile, the ion source can operate at a flow rate of 0.1~2.5 mL/min, further expanding its application range;

Chip liquid chromatography technology, owned by Agilent, is the industry's leading nanoflow liquid chromatography. The nanocurrent separation and the electro spray ionization process are combined to eliminate the volume diffusion outside the column caused by pipeline connection and other factors; At the same time, the enrichment, purification, and separation of samples can be simultaneously completed on the chip, fundamentally and effectively solving the problem of injecting trace samples and high-sensitivity separation and analysis of trace components;

Inert treated platinum plated ion transport capillary eliminates charge accumulation while ensuring no ion loss during polarity switching; Agilent's RF ion lens significantly improves ion transmission at high-quality ends; The vacuum system increases the average free path of ions and reduces the loss of ions during transport to the lowest possible level; The comprehensive application of the above technologies ensures the maximization of ion transport efficiency, thereby significantly improving sensitivity;

The use of high-frequency, small-diameter octapole rods can effectively focus ions into a beam, which is helpful for the high-sensitivity acquisition of MRM;

The high-energy collision hexapole reaction cell using linear acceleration effectively eliminates background noise and "memory effect", thereby ensuring fast and accurate analysis results of trace samples;

The 6410 MS comprehensively applies multiple * technologies mentioned above, thus achieving a femtogram level detection limit; The linear range reaches 106.

2. Accuracy

Automatic tuning: In conjunction with the tuning solution automatic delivery system, software controlled automatic tuning is easy to operate, without the need for other devices or manual operations, maximizing user work efficiency.

3. Flexible and widely applicable

The 6410 MS can be configured with a jet stream ion focusing ion source and chip liquid chromatography, and can also be used in conjunction with various other ion sources from Agilent, such as APCI, APPI, etc., to meet the needs of multiple fields and applications.

Second hand Agilent liquid chromatography-mass spectrometry instrument1200-6410 software features:

A good instrument also requires practical operations such as data acquisition and analysis through software systems to complete the various functions of the instrument itself. The Agilent 6410 MS is equipped with an enhanced version of MassHunter Workstation. For MS applications, the features and advantages of MassHunter Workstation are listed below:

Quantitative analysis parameter automatic optimization - for each submitted compound, the transmission voltage and collision energy are automatically optimized for the selected sub ions; Simplify instrument operation and improve user work efficiency.

Dynamic MRM Data Collection - The collection of MRM data dynamically changes with the elution of chromatographic peaks, reducing the number of monitored compounds in each sampling cycle to the lowest possible level, thereby ensuring that each compound can obtain sufficient sampling time at the peak, significantly improving detection sensitivity and ensuring good reproducibility; Especially suitable for high-sensitivity analysis of multiple components such as food and environment

Quantitative analysis method development function - guides users to accurately, simply, and quickly establish quantitative analysis methods, which can directly import relevant settings in the collection method (such as parent ion and child ion pairs), and can perform necessary validation of the quantitative method before data calculation to avoid omissions in the operation process

Correction Curve Fitting Assistant - Provides multiple fitting line types and weight factors; And directly calculate various line types, calibration equations and their correlation coefficients under different weight factors. Users only need to choose according to their needs, and the software can directly use the selected equation to calculate sample data

Multiple data output formats - convenient for users to use other software for more specialized data calculations or comparisons

Intuitive, flexible, and functionally comprehensive data browsing - simultaneous browsing of multi-component data;

Whether the data meets the experimental requirements without color labeling;

Ionic ratio calculation helps to confirm and judge *;

Flexible reporting - Based on spreadsheets, users can design personalized report templates