SQW-70DI Ultra Low Temperature Crusher

Introduction to Working Principle:

Under the action of external excitation force, the grinding medium undergoes a throwing motion that sometimes disperses and sometimes aggregates. The grinding medium itself rotates in the same direction, while the grinding medium group revolves. The inner and outer grinding media constantly exchange positions, and the two grinding media constantly collide, squeeze, and shear the material, causing it to be crushed and sheared. The particles are constantly broken from large to small. During the crushing process, larger particles are subjected to force first and are crushed first.

According to the working principle, particles composed of plant cell groups, whether composed of large cells or small cell groups, have equal opportunities for compression and impact as long as their overall size is comparable. In the process of crushing medicinal herbs, whether it is large cell groups or small particles

The probability of a cell group being crushed is the same as long as its overall size is equivalent.

The crushing process is fully enclosed and non graded (preservation of drug components)

As is well known, traditional Chinese medicine has complex ingredients, including alkaloids, glycosides, volatile oils, organic acids, flavonoids, etc. These active ingredients often exist in different parts of the drug. For example, ginsenosides have a higher content in the cortex than in the core material, while the starch content in the core material is high. When crushing, the core material is easier to crush than the cortex. If selective crushing is used (i.e. less grinding and more screening), the easily crushed substances will first become micro powders, while the difficult to crush substances will be thrown away as slag. same

The volatile components in the medication will also be carried away with a large amount of gas during pneumatic classification.

At the beginning of its design, the Sanqing Yichen micro powder machine took into account the diversity and complexity of traditional Chinese medicine ingredients. It adopted a multi grinding without screening method in the crushing process, utilizing the third-generation vibration grinding theory (selective crushing of large particles), and operated in a fully enclosed manner without grading to prevent component segregation and loss.

Effective compression and crushing method (increased bioavailability brought by precision compounding)

Due to the force mode of high acceleration impact+shear in this compression crushing method, the material is compressed, torn and crushed under the action of bidirectional composite force. The magnitude of this crushing force is not affected by the material mass, and it is also subjected to large force for materials with small mass. The results of the dissolution test of Ganoderma lucidum polysaccharides after micro crushing with two different force methods for the same batch of Ganoderma lucidum showed that the amount of Ganoderma lucidum polysaccharides dissolved after being crushed by the Sanqing Yichen micro powder machine was 40% higher than that after air flow crushing. There are also significant differences observed in electron microscopy images. This crushing force method will cause lattice damage to the material, and using non compressive crushing method will not destroy the crystal shape no matter how fine it is made. Taking theophylline grinding as an example, the fineness increases after non compression grinding, but the crystal form remains unchanged; When using the Sanqing Yichen micro powder machine for crushing, the original crystal form cannot be seen, and it appears as an amorphous particle composite with a much larger specific surface area than the former.

Solved various problems in traditional Chinese medicine crushing operations

Strong fibrosis（Such as Ganoderma lucidum, licorice, etc） High sugar and high viscosity（Such as goji berries, Ophiopogon japonicus, etc） tree fat Class（Such as frankincense, myrrh, etc）

strong tenacity Sex（Like antelope horns, seahorses, etc）move thing Class（Like scorpions, leeches, etc） mine thing Class（Such as cinnabar, cinnabar, etc）

1Reform of traditional Chinese medicine dosage forms, improvement of efficacy, reduction of dosage, and enhancement of micro powder technology level

New type of Chinese medicine micro powder decoction pieces300Musheng powder soft capsule preparation（Ginseng soft capsules）

One step preparation of ointment（Liuwei Dihuang Soft Capsules）Transdermal (membrane) formulations

Realize granulation and compression without or with minimal auxiliary materials（Wei Ershu）Rate（Minimum 6L equipment: cinnabar per hour25Kg）

For the purpose of reducing dosage and improving efficacy（Rehmanniae Bolus of Eight Ingredients） Reduce medication dosage80%—90%Reforming traditional Chinese medicine decoctions（Tiaoxin Tiaowei Tang）

Reduce the consumption of medicinal herbs（Raspberry reduces losses20%）Low temperature quality crushing, fresh Chinese herbal medicine and fresh animal tissue（Black chicken, crab, etc）

Spray preparation is better than ±1Composite and precision coating with uniformity of ‰(Artificial bezoar)

Technical parameter introduction:

SQW-70DIMedium sized low-temperature production type

Nominal volume:70L

merit Rate:5.5KWElectromagnetic braking type

Power supply voltage:3phase380V

pretend material Quantity:10-20L/time

Operation mode: seat type automatic flipping type

Cooling method: refrigeration machine

comply withGMPStandard

Sanqing Yichen Ultra Low Temperature CrusherThe excellent characteristics ofAnd special performance

A、smashefficient:Suitable for any fibrous, high toughness, high hardness, and moisture content less than 6% material, with low energy consumption and low temperature, avoiding high-temperature oxidation, deterioration, and loss and segregation of active ingredients.Crushing processFully enclosed and dust-freeOverflow, fully improving the working environment.

B、Strong crushing ability ： smashresidue-freeSuitable for both dry and wet crushing, water, alcohol, or other solvents can be added during wet crushing. Suitable for central particle size of150 mesh~10000 mesh（1.3The grinding requirement of (μ m) can reach 1 to 0.1 μ m when using special processes.Materials that require breaking the cell wall of spores such as pollen and Ganoderma spore powderThe wall breaking rate is higher than98% .

C、GMP design:pressGMP design, adopting compliance with drug and food regulationsproductionStandard requirements304Made of stainless steel,The contact area with the material isPolished stainless steel，The internal corners and arcs are excessive, and the fully enclosed operation has no dust pollution or material loss.

DEasy to operate:Compact and reasonable structure with small footprint, no need for air compressors, conveying pipelines, dust removal and collection devices, and can be put into operation by connecting water and electricity.Easy to assemble, disassemble, and replace materials; Can be cleaned and disinfected with water, starch, alcohol, etc; Equipped with a composite soundproof cover, the production noise is low.

EEasy to operate:Low labor intensity, easy to operate, convenient for disassembly, cleaning, and daily maintenance.

FComplete range of models:There are both large and medium-sized equipment suitable for industrial production, as well as small equipment suitable for small-scale production or scientific research experiments.

GApplication scope:Suitable for animals with different variety characteristics and significant differences(Plants), mineral medicinal materials, and (health) food raw materials, such as materials with toughness, brittleness, high (low) hardness, high fiber content, high oil content, or high sugar content.

HAppearance：Stainless steel fully enclosed, made of matte stainless steel plate.

I、Precision coating ：Can produce particles of two or more materialsPrecision compounding and coatingHigh solid content, strong homogenization, and super emulsification operations.

J、Low temperature quality crushing, crushing fresh Chinese herbs and animal fresh tissues.

KTemperature controllable ：The crushing temperature can be controlled by adjusting the temperature and flow rate of the cooling water. When low-temperature crushing is required, a refrigeration system should be configuredThe minimum temperature can reach -35℃.

Other process application methods

1. Application in the cosmetics industry: After the cell wall is broken by Sanqing Yichen micro pulverization, the onset time is short, the absorption is more complete, the efficacy is more comprehensive, and the effect is more obvious. Some fresh medicines can also be crushed and directly made into cosmetics.

2. Application in the animal medicine industry: Sanqing Yichen micro powder technology is an effective means of implementing green animal medicine. (Traditional Chinese medicine) animal medicine can effectively improve efficacy, reduce costs, solve drug residues, and improve safety after cell wall breaking. Chinese medicine micro powder quickly disperses and suspends in water, and is supplied to livestock for normal drinking through an automatic water dispenser, effectively solving the problems of drug precipitation and uneven dosage that lead to reduced efficacy.

3. The application of precious fine materials, without loss, truly achieves "limited resources, maximum utilization".

4. Precision mixing (achieving composite and precision coating with uniformity better than ± 1 ‰)

5. The impact on molding (including coating)

1) For tablets and capsules, improve dissolution rate and enhance bioavailability; Improve appearance and uniformity of particle content; Reduced fiber elasticity makes it easier to pelletize and compress; Increase the specific gravity of the capsule to increase its filling capacity;

2) For soft capsules, improve the mixing uniformity between the main drug and the matrix, and reduce sedimentation; Due to the increase in the particle size of the main drug, the amount of matrix used can be correspondingly reduced, thereby lowering costs; Equal volume particles, thixotropy, particle size distribution, compression crushing.

3) For ointment, gel and other external preparations, improve the mixing uniformity of the main drug and the matrix; Improve the delicacy of appearance; Reduced granularity,

Facilitating transdermal absorption and improving therapeutic efficacy;