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E-mail
dawei.zhao@aichrom.com
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Phone
15210979260
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Address
No.1 Zhongguancun North Second Street, Haidian District, Beijing
Product Categories
Ningbo Aichun Biotechnology Co., Ltd
SPR molecular interactor
NegotiableUpdate on 02/02
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Overview
The AiSPR-96 SPR molecular interactor has a wide wavelength range, meeting various application needs such as molecular interaction, kinetics, protein quantification, enzyme activity determination, ELISA experiments, and cell detection.
Product Details
AiSPR-96SPR molecular interactorMain Features
1. 96 flux can meet large-scale detection needs, and can also be used for local hole selection or jump hole detection, making it flexible to use
2. 8-channel light absorption can be quickly measured with high accuracy and good repeatability
3. Wide wavelength range, meeting various application needs such as molecular interaction, kinetics, protein quantification, enzyme activity determination, ELISA experiments, cell detection, etc
4. A supporting software analysis platform that enables one-stop data processing
5. Compact and portable instrument structure design
As a label free biomolecule interaction analyzer, AiSPR-96 no longer limits the molecular weight of organic compounds. You can analyze sensitive or rare samples, accurately obtain data on extremely fast binding or very slow dissociation, and reliably reveal small differences in kinetics.
AiSPR-96 is a 96 well plate biomolecule interaction analyzer based on SPR technology, which can achieve real-time analysis without labeling, providing you with high-quality kinetic, affinity, antibody screening, and concentration determination information. AiSPR-96 can accurately distinguish concentration differences at the picomolar level, allowing you to directly measure intermolecular interactions in the natural state of the sample without the need for some inferior alternative methods. AiSPR-96 provides valuable information on intermolecular interactions between biomolecules for various application fields, from basic scientific research, small molecule and biopharmaceutical development, to vaccine development and quality control.
Detailed analysis of intermolecular interactions is not simply described as the strength of affinity. By parsing affinity into real-time kinetic data, we can gain a deeper understanding of biological phenomena and make the connection between intermolecular interactions and their functions clearer.
AiSPR-96SPR molecular interactorThe extended dynamic space provided brings you tangible benefits, as you can obtain high-quality information related to interactions between biomolecules. Even for highly dynamic interactions, such as extremely fast binding processes and extremely slow dissociation processes, you can confidently measure them. You can accurately determine the true dissociation rate of antibody complexes with strong affinity, which is crucial for optimizing drug efficacy. You may also be able to capture subtle behavioral differences between rapidly binding molecules, which will help you screen for better drugs, especially when the physiological activity concentration is low after drug use.
Basic Parameters
Size (length x depth x height) |
370 × 210 × 140 mm |
Weight (excluding computer) |
2.8 kg |
power supply |
100–240 VAC, 50/60 Hz |
interface |
USB |
performance parameters
Detection Principle |
Surface Plasmon Resonance (SPR) Technology |
Detection Application |
Dynamics/affinity characterization, dynamics/affinity screening, single cycle dynamics, small molecule interaction analysis, fragment drug screening, epitope identification, pairing screening, immunogenicity, quantitative analysis, thermodynamics, ELISA, and enzyme-linked immunosorbent assay detection functions, etc |
Sample Type |
Buffer solution containing DMSO, purified samples, plasma and serum, cell supernatant, lysis buffer, small molecule candidate drugs, high molecular weight protein antibodies, peptides, DNA, RNA, polysaccharides, lipids, cells, and viruses, etc |
Optical channel |
8 fiber optic detection channels |
flux |
96, up to 8 parallel determinations |
refractive index |
1.33-1.40 |
sample volume |
2 μL - 200 μL |
Oscillation speed |
200-1200 rpm |
Minimum detection limit |
200 Da |
Detection Time |
Conduct affinity testing on 8 samples for less than 10 minutes; Dynamic screening can simultaneously test up to 96 samples, with a minimum analysis time of 5 minutes. The data is sorted according to the size of the combined signal |
Baseline noise (RMS) |
< 0.1 RU |
baseline drift |
< 0.5 RU/min |
Sample size for testing |
Up to 96 samples can be measured simultaneously |
Concentration detection range |
0.05-1000 μg/mL |
Testing time (typical) |
96 samples can be quantitatively tested for human IgG in just 5 minutes |
The data shows |
Display real-time dynamics combined with curve graphs, fitting result graphs, concentration data analysis, including calibration curves and output of concentration data lists, kinetic data lists, epitope identification graphs, bar charts, etc |
Export file |
EXCEL、TXT |
Chip sensor
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